Dr. Diego Serra
Diego Serra earned a Licentiate degree in Biotechnology from the University of Litoral (Argentina) and a PhD degree in Biological Science from the University of La Plata (Argentina).
From 2011 to 2019 he worked as postdoctoral researcher (funded by the Alexander von Humboldt Foundation) and as teaching assistant in the group of Prof. Regine Hengge at Humboldt University of Berlin. His research focused on understanding the role of extracellular matrix components on shaping the structure of Escherichia coli biofilms.
Since 2019 he is a research Group Leader at the Institute of Molecular and Cell Biology of Rosario (Argentina) and member of the National Research Council (CONICET) of Argentina. He is currently interested in understanding how bacterial cells inside biofilms tolerate antibiotic treatments.
Instituto de Biología Molecular y Celular de Rosario (IBR-CONICET)
Predio CONICET Rosario, Ocampo y Esmeralda
(2000) Rosario
Argentina
Articles
Serra, D. O., Hengge, R. 2019. »A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms.« Journal of Molecular Biology, 431, (23): 4775-4793. https://doi.org/10.1016/j.jmb.2019.04.001
Klauck, G., Serra, D. O., Possling, A., Hengge, R. 2018. »Spatial organization of different sigma factor activities and c-di-GMP signalling within the three-dimensional landscape of a bacterial biofilm.« Open Biology, 8, (8): 180066. https://doi.org/10.1098/rsob.180066
Thongsomboon, W., Serra, D. O., Possling, A., Hadjineophytou, C., Hengge, R., Cegelski, L. 2018. »Phosphoethanolamine cellulose: A naturally produced chemically modified cellulose.« Science, 359, (6373): 334-338. https://doi.org/10.1126/science.aao4096
Serra, D. O., Mika, F., Richter, A. M., Hengge, R. 2016. »The green tea polyphenol EGCG inhibits E. coli biofilm formation by impairing amyloid curli fibre assembly and downregulating the biofilm regulator CsgD via the σ E‐dependent sRNA RybB.« Molecular Microbiology, 101, (1): 136-151. https://doi.org/10.1111/mmi.13379
Serra, D. O., Richter, A. M., Hengge, R. 2013. »Cellulose as an Architectural Element in Spatially Structured Escherichia coli Biofilms.« Journal of Bacteriology, 195, (24): 5540-5554. https://doi.org/10.1128/JB.00946-13