Prof. Dr. Regine Hengge - Matters of Activity

Regine Hengge studied Biology and obtained her doctorate at Universität Konstanz. After a post-doctoral phase at Princeton University (NJ, USA), she completed her Habilitation in Microbiology and Molecular Genetics at Universität Konstanz.

As a Full Professor she headed the microbiology unit of Freie Universität Berlin from 1998-2013, and since 2013 has been in a similar position at Humboldt-Universität zu Berlin.

As a Principal Investigator at »Matters of Activity«, she is studying bacterial biofilms as an example of active matter with a focus on nano/micro-architecture and morphogenesis of biofilms.

For her scientific research Regine Hengge received the Gottfried Wilhelm Leibniz Prize and an ERC Advanced Investigator Grant. She is an elected member of Leopoldina, EMBO and other national and international academies.

Field

Microbiology & Molecular Genetics

Roles

Member of the Executive Board

Projects

Weaving (Project Leader)
Symbolic Material (Principal Investigator)

Telephone

+49 30 2093 49686

Email Address

regine.hengge [at] hu-berlin.de

Website

http://mikrobiologie.hu-berlin.de/hengge

Address

Department of Biology / Microbiology
Humboldt-Universität zu Berlin
Philippstr. 13 - House 22
10115 Berlin

Publications

Hengge, R. 2021. »High-Specificity Local and Global c-di-GMP Signaling.« Trends in Microbiology.
https://doi.org/10.1016/j.tim.2021.02.003

Hengge, R. 2020. »Linking bacterial growth, survival, and multicellularity – small signaling molecules as triggers and drivers.« Current Opinion in Microbiology, 55: 57-66.
https://doi.org/10.1016/j.mib.2020.02.007

Pruteanu, M., Hernández Lobato, J. I., Stach, T., Hengge, R. 2020. »Common plant flavonoids prevent the assembly of amyloid curli fibres and can interfere with bacterial biofilm formation.« Environmental Microbiology, 22: 5280-5299.
https://doi.org/10.1111/1462-2920.15216

Pfiffer, V., Sarenko, O., Possling, A., Hengge, R. 2019. »Genetic dissection of Escherichia coli's master diguanylate cyclase DgcE: Role of the N-terminal MASE1 domain and direct signal input from a GTPase partner system.« PLoS Genet, 15 (4): e1008059.
https://doi.org/10.1371/journal.pgen.1008059

Thongsomboon, W., Serra, D. O., Possling, A., Hadjineophytou, C., Hengge, R., Cegelski, L. 2018. »Phosphoethanolamine cellulose: A naturally produced chemically modified cellulose.« Science, 359 (6373): 334-338.
https://doi.org/10.1126/science.aao4096

Top selected → show all

Articles in Edited Volumes

Hengge, R., Krauthausen, K. 2023. »The Event of a Fiber.« In Architectures of Weaving: From Fibers and Yarns to Scaffolds and Skins, edited by Sauer, C., Stoll, M., Fransén Waldhör, E., Schneider, M. Berlin: Jovis Verlag GmbH, 22-28.

Hengge, R., Krauthausen, K. 2021. »Das Ereignis der Faser.« In Hella Jongerius: Kosmos Weben, edited by Rosenthal, S., Meister, C. Berlin: Gropius Bau, 48-53.

Hengge, R., Krauthausen, K. 2021. »The Event of a Fibre.« In Hella Jongerius: Woven Cosmos, edited by Rosenthal, S., Meister, C. Berlin: Gropius Bau, 54-59.

Hengge, R. 2019. »Durch den Datendschungel auf der Suche nach Erkenntnis: Experimentieren in der molekularen Mikrobiologie.« In Experimentieren. Einblicke in Praktiken und Versuchsaufbauten zwischen Wissenschaft und Gestaltung, edited by Margin, S.H., Rabe, W., Schäffner, W., Schmirgel, F. transcript Verlag, 123-135.
https://doi.org/10.14361/9783839446386-fm

Serra, D. O., Hengge, R. 2019. »Cellulose in Bacterial Biofilms.« Cham: Springer International Publishing, 355-392.
https://doi.org/10.1007/978-3-030-12919-4_8

Serra, D. O., Hengge, R. 2017. »Experimental Detection and Visualization of the Extracellular Matrix in Macrocolony Biofilms.« Methods in Molecular Biology. 1657, New York: Springer, 133-145.
https://doi.org/10.1007/978-1-4939-7240-1_11

Hengge, R., Grosser, G. 2014. »Science & Theatre – ein Experiment an der Schnittstelle von Naturwissenschaft und Kunst.« In ArteFakte: Wissen ist Kunst – Kunst ist Wissen. Reflexionen und Praktiken wissenschaftlich-künstlerischer Begegnungen (Kultur- und Medientheorie), edited by Parzinger, H., Aue, S., Stock, G. Bielefeld: transcript, 479-488.

Pesavento, C., Hengge, R. 2010. »c‐di‐GMP Signaling.« In Bacterial Signaling, edited by Krämer, R., Jung, K. Weinheim: WILEY-VCH Verlag GmbH & Co. KGaA, 377-394.
https://doi.org/10.1002/9783527629237.ch21

Hengge, R. 2008. »The Two-Component Network and the General Stress Sigma Factor RpoS (σS) in Escherichia coli.« Advances in Experimental Medicine and Biology. 631, New York: Springer, 40-53.
https://doi.org/10.1007/978-0-387-78885-2_4

Articles

Hengge, R., Pruteanu, M., Stülke, J., Tschowri, N., Turgay, K. 2023. »Recent advances and perspectives in nucleotide second messenger signaling in bacteria.« microLife, 4: uqad015.
https://doi.org/10.1093/femsml/uqad015

Junkermeier, E. H., Hengge, R. 2023. »Local signaling enhances output specificity of bacterial c-di-GMP signaling networks.« In Nucleotide Second Messengers in Prokaryotes, special issue. microLife, 4: uqad026.
https://doi.org/10.1093/femsml/uqad026

Hengge, R. 2022. »Non-Human Others – a Message from the Planetary Invisibles.« ISSN 2701-2557. Gastgarten, 3 (1/2022): 24-29.

Hengge, R. 2021. »High-Specificity Local and Global c-di-GMP Signaling.« Trends in Microbiology.
https://doi.org/10.1016/j.tim.2021.02.003

Junkermeier, E. H., Hengge, R. 2021. »A Novel Locally c-di-GMP-Controlled Exopolysaccharide Synthase Required for Bacteriophage N4 Infection of Escherichia coli.« mBio, 12 (6): e0324921.
https://doi.org/10.1128/mbio.03249-21

Serra, D. O., Hengge, R. 2021. »Bacterial Multicellularity: The Biology of Escherichia coli Building Large-Scale Biofilm Communities.« Annual Review of Microbiology, 75 (1)
https://doi.org/10.1146/annurev-micro-031921-055801

Ziege, R., Tsirigoni, A., Large, B., Serra, D. O., Blank, K. G., Hengge, R., Fratzl, P., Bidan, C. M. 2021. »Adaptation of Escherichia coli Biofilm Growth, Morphology, and Mechanical Properties to Substrate Water Content.« ACS Biomaterials Science & Engineering, 7 (11): 5315-5325.
https://doi.org/10.1021/acsbiomaterials.1c00927

Hengge, R. 2020. »Crosstalking second messengers.« Nature Microbiology, 6 (1): 9-10.
https://doi.org/10.1038/s41564-020-00842-3

Pruteanu, M., Hernández Lobato, J. I., Stach, T., Hengge, R. 2020. »Common plant flavonoids prevent the assembly of amyloid curli fibres and can interfere with bacterial biofilm formation.« Environmental Microbiology, 22 (12): 5280-5299.
https://doi.org/10.1111/1462-2920.15216

Richter, A. M., Possling, A., Malysheva, N., Yousef, K. P., Herbst, S., von Kleist, M., Hengge, R. 2020. »Local c-di-GMP Signaling in the Control of Synthesis of the E. coli Biofilm Exopolysaccharide pEtN-Cellulose.« Journal of Molecular Biology, 432 (16): 4576-4595.
https://doi.org/10.1016/j.jmb.2020.06.006

Rodríguez-Rojas, A., Kim, J. J., Johnston, P. R., Makarova, O., Eravci, M., Weise, C., Hengge, R., Rolff, J. 2020. »Non-lethal exposure to H2O2 boosts bacterial survival and evolvability against oxidative stress.« PLOS Genetics, 16 (3): e1008649.
https://doi.org/10.1371/journal.pgen.1008649

Hengge, R. 2019. »Spotlight on… Regine Hengge.« FEMS Microbiology Letters, 366 (2): fny293.
https://doi.org/10.1093/femsle/fny293

Hengge, R. 2019. »Targeting Bacterial Biofilms by the Green Tea Polyphenol EGCG.« Molecules, 24 (13): 2403.
https://doi.org/10.3390/molecules24132403

Kettles, R. A., Tschowri, N., Lyons, K. J., Sharma, P., Hengge, R., Webber, M. A., Grainger, D. C. 2019. »The Escherichia coli MarA protein regulates the ycgZ-ymgABC operon to inhibit biofilm formation.« Molecular Microbiology, 112 (5): 1609-1625.
https://doi.org/10.1111/mmi.14386

Serra, D. O., Hengge, R. 2019. »A c-di-GMP-Based Switch Controls Local Heterogeneity of Extracellular Matrix Synthesis which Is Crucial for Integrity and Morphogenesis of Escherichia coli Macrocolony Biofilms.« Journal of Molecular Biology, 431 (23): 4775-4793.
https://doi.org/10.1016/j.jmb.2019.04.001

Herbst, S., Lorkowski, M., Sarenko, O., Nguyen, T. K. L., Jaenicke, T., Hengge, R. 2018. »Transmembrane redox control and proteolysis of PdeC, a novel type of c‐di‐GMP phosphodiesterase.« The EMBO Journal, 37 (8)
https://doi.org/10.15252/embj.201797825

Klauck, G., Serra, D. O., Possling, A., Hengge, R. 2018. »Spatial organization of different sigma factor activities and c-di-GMP signalling within the three-dimensional landscape of a bacterial biofilm.« Open Biology, 8 (8): 180066.
https://doi.org/10.1098/rsob.180066

Midha, A., Janek, K., Niewienda, A., Henklein, P., Guenther, S., Serra, D. O., Schlosser, J., Hengge, R., Hartmann, S. 2018. »The Intestinal Roundworm Ascaris suum Releases Antimicrobial Factors Which Interfere With Bacterial Growth and Biofilm Formation.« Frontiers in Cellular and Infection Microbiology, 8 (AUG): 271.
https://doi.org/10.3389/fcimb.2018.00271

Sarenko, O., Klauck, G., Wilke, F. M., Pfiffer, V., Richter, A. M., Herbst, S., Kaever, V., Hengge, R. 2017. »More than Enzymes That Make or Break Cyclic Di-GMP—Local Signaling in the Interactome of GGDEF/EAL Domain Proteins of Escherichia coli.« mBio, 8 (5)
https://doi.org/10.1128/mBio.01639-17

Hengge, R. 2016. »Trigger phosphodiesterases as a novel class of c-di-GMP effector proteins.« Philosophical Transactions of the Royal Society B: Biological Sciences, 371 (1707): 20150498.
https://doi.org/10.1098/rstb.2015.0498

Serra, D. O., Mika, F., Richter, A. M., Hengge, R. 2016. »The green tea polyphenol EGCG inhibits E. coli biofilm formation by impairing amyloid curli fibre assembly and downregulating the biofilm regulator CsgD via the σ E‐dependent sRNA RybB.« Molecular Microbiology, 101 (1): 136-151.
https://doi.org/10.1111/mmi.13379

Hengge, R., Galperin, M. Y., Ghigo, J., Gomelsky, M., Green, J., Hughes, K. T., Jenal, U., Landini, P. 2015. »Systematic Nomenclature for GGDEF and EAL Domain-Containing Cyclic Di-GMP Turnover Proteins of Escherichia coli.« Journal of Bacteriology, 198 (1): 7-11.
https://doi.org/10.1128/JB.00424-15

Hengge, R., Gründling, A., Jenal, U., Ryan, R., Yildiz, F. 2015. »Bacterial Signal Transduction by Cyclic Di-GMP and Other Nucleotide Second Messengers.« Journal of Bacteriology, 198 (1): 15-26.
https://doi.org/10.1128/JB.00331-15

Hengge, R. 2015. »Bakterielle Megastädte.« BIOspektrum, 21 (5): 480-483.
https://doi.org/10.1007/s12268-015-0603-x

Povolotsky, T. L., Hengge, R. 2015. »Genome-Based Comparison of Cyclic Di-GMP Signaling in Pathogenic and Commensal Escherichia coli Strains.« Journal of Bacteriology, 198 (1): 111-126.
https://doi.org/10.1128/JB.00520-15

Serra, D. O., Klauck, G., Hengge, R. 2015. »Vertical stratification of matrix production is essential for physical integrity and architecture of macrocolony biofilms of Escherichia coli.« Environmental Microbiology, 17 (12): 5073-5088.
https://doi.org/10.1111/1462-2920.12991

Yousef, K. P., Streck, A., Schütte, C., Siebert, H., Hengge, R., Kleist, M. v. 2015. »Logical-continuous modelling of post-translationally regulated bistability of curli fiber expression in Escherichia coli.« BMC Systems Biology, 9 (1)
https://doi.org/10.1186/s12918-015-0183-x

Mika, F., Hengge, R. 2014. »Small RNAs in the control of RpoS, CsgD, and biofilm architecture of Escherichia coli.« RNA Biology, 11 (5): 494-507.
https://doi.org/10.4161/rna.28867

Richter, A. M., Povolotsky, T. L., Wieler, L. H., Hengge, R. 2014. »Cyclic‐di‐ GMP signalling and biofilm‐related properties of the Shiga toxin‐producing 2011 German outbreak E scherichia coli O104:H4.« EMBO Molecular Medicine, 6 (12): 1622-1637.
https://doi.org/10.15252/emmm.201404309

Serra, D. O., Hengge, R. 2014. »Stress responses go three dimensional – the spatial order of physiological differentiation in bacterial macrocolony biofilms.« Environmental Microbiology, 16 (6): 1455-1471.
https://doi.org/10.1111/1462-2920.12483

Hengge, R., Sourjik, V. 2013. »Bacterial regulatory networks—from self‐organizing molecules to cell shape and patterns in bacterial communities.« EMBO reports, 14 (8): 667-669.
https://doi.org/10.1038/embor.2013.93

Hengge, R. 2013. »Novel tricks played by the second messenger c-di-GMP in bacterial biofilm formation.« The EMBO Journal, 32 (3): 322-323.
https://doi.org/10.1038/emboj.2012.351

Hengge, R. 2013. »Reply to "precedence for the structural role of flagella in biofilms".« mBio, 4 (2)
https://doi.org/10.1128/mBio.00245-13

Lindenberg, S., Klauck, G., Pesavento, C., Klauck, E., Hengge, R. 2013. »The EAL domain protein YciR acts as a trigger enzyme in a c-di-GMP signalling cascade in E. coli biofilm control.« The EMBO Journal, 32 (14): 2001-2014.
https://doi.org/10.1038/emboj.2013.120

Mika, F., Hengge, R. 2013. »Small regulatory RNAs in the control of motility and biofilm formation in E. coli and Salmonella.« International Journal of Molecular Sciences, 14 (3): 4560-4579.
https://doi.org/10.3390/ijms14034560

Serra, D. O., Richter, A. M., Hengge, R. 2013. »Cellulose as an Architectural Element in Spatially Structured Escherichia coli Biofilms.« Journal of Bacteriology, 195 (24): 5540-5554.
https://doi.org/10.1128/JB.00946-13

Serra, D. O., Richter, A. M., Klauck, G., Mika, F., Hengge, R. 2013. »Microanatomy at Cellular Resolution and Spatial Order of Physiological Differentiation in a Bacterial Biofilm.« mBio, 4 (2): e00103-13.
https://doi.org/10.1128/mBio.00103-13

Karch, H., Denamur, E., Dobrindt, U., Finlay, B. B., Hengge, R., Johannes, L., Ron, E. Z., Tønjum, T., Sansonetti, P. J., Vicente, M. 2012. »The enemy within us: lessons from the 2011 European Escherichia coli O104:H4 outbreak.« EMBO Molecular Medicine, 4 (9): 841-848.
https://doi.org/10.1002/emmm.201201662

Mika, F., Busse, S., Possling, A., Berkholz, J., Tschowri, N., Sommerfeldt, N., Pruteanu, M., Hengge, R. 2012. »Targeting of csgD by the small regulatory RNA RprA links stationary phase, biofilm formation and cell envelope stress in Escherichia coli.« Molecular Microbiology, 84 (1): 51-65.
https://doi.org/10.1111/j.1365-2958.2012.08002.x

Pesavento, C., Hengge, R. 2012. »The global repressor FliZ antagonizes gene expression by σ S -containing RNA polymerase due to overlapping DNA binding specificity.« Nucleic Acids Research, 40 (11): 4783-4793.
https://doi.org/10.1093/nar/gks055

Povolotsky, T. L., Hengge, R. 2012. »‘Life-style’ control networks in Escherichia coli: Signaling by the second messenger c-di-GMP.« Journal of Biotechnology, 160 (1-2): 10-16.
https://doi.org/10.1016/j.jbiotec.2011.12.024

Tschowri, N., Lindenberg, S., Hengge, R. 2012. »Molecular function and potential evolution of the biofilm‐modulating blue light‐signalling pathway of Escherichia coli.« Molecular Microbiology, 85 (5): 893-906.
https://doi.org/10.1111/j.1365-2958.2012.08147.x

Hengge, R. 2011. »Stationary-Phase Gene Regulation in Escherichia coli§.« EcoSal Plus, 4 (2)
https://doi.org/10.1128/ecosalplus.5.6.3

Kolmsee, T., Hengge, R. 2011. »Rare codons play a positive role in the expression of the stationary phase sigma factor RpoS (σS) in Escherichia coli.« RNA Biology, 8 (5): 913-921.
https://doi.org/10.4161/rna.8.5.16265

Singh, S. S., Typas, A., Hengge, R., Grainger, D. C. 2011. »Escherichia coli σ70 senses sequence and conformation of the promoter spacer region.« Nucleic Acids Research, 39 (12): 5109-5118.
https://doi.org/10.1093/nar/gkr080

Hengge, R. 2010. »Cyclic-di-GMP reaches out into the bacterial RNA world.« Science Signaling, 3 (149): pe44-pe44.
https://doi.org/10.1126/scisignal.3149pe44

Basineni, S. R., Madhugiri, R., Kolmsee, T., Hengge, R., Klug, G. 2009. »The influence of Hfq and ribonucleases on the stability of the small non-coding RNA OxyS and its target rpoS in E. coli is growth phase dependent.« RNA Biology, 6 (5): 584-594.
https://doi.org/10.4161/rna.6.5.10082

Hengge, R., Turgay, K. 2009. »Proteolysis in prokaryotes – from molecular machines to a systems perspective.« Research in Microbiology, 160 (9): 615-617.
https://doi.org/10.1016/j.resmic.2009.09.007

Hengge, R. 2009. »Principles of c-di-GMP signalling in bacteria.« Nature Reviews Microbiology, 7 (4): 263-273.
https://doi.org/10.1038/nrmicro2109

Hengge, R. 2009. »Proteolysis of σS (RpoS) and the general stress response in Escherichia coli.« Research in Microbiology, 160 (9): 667-676.
https://doi.org/10.1016/j.resmic.2009.08.014

Pesavento, C., Hengge, R. 2009. »Bacterial nucleotide-based second messengers.« Current Opinion in Microbiology, 12 (2): 170-176.
https://doi.org/10.1016/j.mib.2009.01.007

Sommerfeldt, N., Possling, A., Becker, G., Pesavento, C., Tschowri, N., Hengge, R. 2009. »Gene expression patterns and differential input into curli fimbriae regulation of all GGDEF/EAL domain proteins in Escherichia coli.« Microbiology, 155 (4): 1318-1331.
https://doi.org/10.1099/mic.0.024257-0

Tschowri, N., Busse, S., Hengge, R. 2009. »The BLUF-EAL protein YcgF acts as a direct anti-repressor in a blue-light response of Escherichia coli.« Genes & Development, 23 (4): 522-534.
https://doi.org/10.1101/gad.499409

Heuveling, J., Possling, A., Hengge, R. 2008. »A role for Lon protease in the control of the acid resistance genes of Escherichia coli.« Molecular Microbiology, 69 (2): 534-547.
https://doi.org/10.1111/j.1365-2958.2008.06306.x

Pesavento, C., Becker, G., Sommerfeldt, N., Possling, A., Tschowri, N., Mehlis, A., Hengge, R. 2008. »Inverse regulatory coordination of motility and curli-mediated adhesion in Escherichia coli.« Genes & Development, 22 (17): 2434-2446.
https://doi.org/10.1101/gad.475808

Barembruch, C., Hengge, R. 2007. »Cellular levels and activity of the flagellar sigma factor FliA ofEscherichia coliare controlled by FlgM-modulated proteolysis.« Molecular Microbiology, 65 (1): 76-89.
https://doi.org/10.1111/j.1365-2958.2007.05770.x

Klauck, E., Typas, A., Hengge, R. 2007. »The σS subunit of RNA polymerase as a signal integrator and network master regulator in the general stress response in Escherichia coli.« Science Progress, 90 (2-3): 103-127.
https://doi.org/10.3184/003685007X215922

Obrist, M., Milek, S., Klauck, E., Hengge, R., Narberhaus, F. 2007. »Region 2.1 of the Escherichia coli heat-shock sigma factor RpoH (σ32) is necessary but not sufficient for degradation by the FtsH protease.« Microbiology, 153 (8): 2560-2571.
https://doi.org/10.1099/mic.0.2007/007047-0

Typas, A., Barembruch, C., Possling, A., Hengge, R. 2007. »Stationary phase reorganisation of the Escherichia coli transcription machinery by Crl protein, a fine-tuner of σs activity and levels.« The EMBO Journal, 26 (6): 1569-1578.
https://doi.org/10.1038/sj.emboj.7601629

Typas, A., Becker, G., Hengge, R. 2007. »The molecular basis of selective promoter activation by the ?Ssubunit of RNA polymerase.« Molecular Microbiology, 63 (5): 1296-1306.
https://doi.org/10.1111/j.1365-2958.2007.05601.x

Typas, A., Stella, S., Johnson, R. C., Hengge, R. 2007. »The -35 sequence location and the Fis-sigma factor interface determine sigmas selectivity of the proP (P2) promoter in Escherichia coli.« Molecular Microbiology, 63 (3): 780-796.
https://doi.org/10.1111/j.1365-2958.2006.05560.x

Santos, J. M., Freire, P., Mesquita, F. S., Mika, F., Hengge, R., Arraiano, C. M. 2006. »Poly(A)-polymerase I links transcription with mRNA degradation via sigmaS proteolysis.« Molecular Microbiology, 60 (1): 177-188.
https://doi.org/10.1111/j.1365-2958.2006.05078.x

Typas, A., Hengge, R. 2006. »Role of the spacer between the -35 and -10 regions in sigmas promoter selectivity in Escherichia coli.« Molecular Microbiology, 59 (3): 1037-1051.
https://doi.org/10.1111/j.1365-2958.2005.04998.x

Weber, H., Pesavento, C., Possling, A., Tischendorf, G., Hengge, R. 2006. »Cyclic-di-GMP-mediated signalling within the sigma network of Escherichia coli.« Molecular Microbiology, 62 (4): 1014-1034.
https://doi.org/10.1111/j.1365-2958.2006.05440.x

Klauck, E., Becker, G., Hengge, R. 2005. »Proteolysis as regulatory principle in prokaryotes.« BioSpektrum, 11 (2): 166.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-17844402997&partnerID=40&md5=2faa32fb7676cef244550ba08ad00852

Mika, F., Hengge, R. 2005. »A two-component phosphotransfer network involving ArcB, ArcA, and RssB coordinates synthesis and proteolysis of S (RpoS) in E. coli.« Genes & Development, 19 (22): 2770-2781.
https://doi.org/10.1101/gad.353705

Weber, H., Polen, T., Heuveling, J., Wendisch, V. F., Hengge, R. 2005. »Genome-Wide Analysis of the General Stress Response Network in Escherichia coli: σS-Dependent Genes, Promoters, and Sigma Factor Selectivity.« Journal of Bacteriology, 187 (5): 1591-1603.
https://doi.org/10.1128/JB.187.5.1591-1603.2005

Hengge, R., Gourse, R. L. 2004. »Cell regulation.« Current Opinion in Microbiology, 7 (2): 99-101.
https://doi.org/10.1016/j.mib.2004.02.016

Typas, A., Hengge, R. 2004. »Differential ability of σs and σ70 of Escherichia coli to utilize promoters containing half or full UP-element sites.« Molecular Microbiology, 55 (1): 250-260.
https://doi.org/10.1111/j.1365-2958.2004.04382.x

Hengge, R., Bukau, B. 2003. »Proteolysis in prokaryotes: protein quality control and regulatory principles.« Molecular Microbiology, 49 (6): 1451-1462.
https://doi.org/10.1046/j.1365-2958.2003.03693.x

Jenal, U., Hengge-Aronis, R. 2003. »Regulation by proteolysis in bacterial cells.« Current Opinion in Microbiology, 6 (2): 163-172.
https://doi.org/10.1016/S1369-5274(03)00029-8

Metzner, M., Germer, J., Hengge, R. 2003. »Multiple stress signal integration in the regulation of the complex σS-dependent csiD-ygaF-gabDTP operon in Escherichia coli.« Molecular Microbiology, 51 (3): 799-811.
https://doi.org/10.1046/j.1365-2958.2003.03867.x

Stephani, K., Weichart, D., Hengge, R. 2003. »Dynamic control of Dps protein levels by ClpXP and ClpAP proteases in Escherichia coli.« Molecular Microbiology, 49 (6): 1605-1614.
https://doi.org/10.1046/j.1365-2958.2003.03644.x

Stüdemann, A. 2003. »Sequential recognition of two distinct sites in sigma(S) by the proteolytic targeting factor RssB and ClpX.« The EMBO Journal, 22 (16): 4111-4120.
https://doi.org/10.1093/emboj/cdg411

Weichart, D., Querfurth, N., Dreger, M., Hengge-Aronis, R. 2003. »Global Role for ClpP-Containing Proteases in Stationary-Phase Adaptation of Escherichia coli.« Journal of Bacteriology, 185 (1): 115-125.
https://doi.org/10.1128/JB.185.1.115-125.2003

Becker, G., Klauck, E., Hengge-Aronis, R. 2002. »The response regulator RssB, a recognition factor for σS proteolysis in Escherichia coli, can act like an anti-σS factor.« Molecular Microbiology, 35 (3): 657-666.
https://doi.org/10.1046/j.1365-2958.2000.01736.x

Hengge-Aronis, R. 2002. »Recent insights into the general stress response regulatory network in Escherichia coli.« Journal of Molecular Microbiology and Biotechnology, 4 (3): 341.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0036198628&partnerID=40&md5=e3f923059ff593f9069fd4e73f225bc2

Hengge-Aronis, R. 2002. »Signal transduction and regulatory mechanisms involved in control of the σS (RpoS) subunit of RNA polymerase.« Microbiology and Molecular Biology Reviews, 66 (3): 373-395.
https://doi.org/10.1128/MMBR.66.3.373-395.2002

Hengge-Aronis, R. 2002. »Stationary phase gene regulation: what makes an Escherichia coli promoter σS-selective?« Current Opinion in Microbiology, 5 (6): 591-595.
https://doi.org/10.1016/S1369-5274(02)00372-7

Pruteanu, M., Hengge-Aronis, R. 2002. »The cellular level of the recognition factor RssB is rate-limiting for σS proteolysis: implications for RssB regulation and signal transduction in σS turnover in Escherichia coli.« Molecular Microbiology, 45 (6): 1701-1713.
https://doi.org/10.1046/j.1365-2958.2002.03123.x

Balandina, A., Claret, L., Hengge-Aronis, R., Rouviere-Yaniv, J. 2001. »The Escherichia coli histone-like protein HU regulates rpoS translation.« Molecular Microbiology, 39 (4): 1069-1079.
https://doi.org/10.1046/j.1365-2958.2001.02305.x

Becker, G., Hengge-Aronis, R. 2001. »What makes an Escherichia coli promoter σS dependent? Role of the -13/-14 nucleotide promoter positions and region 2.5 of σS.« Molecular Microbiology, 39 (5): 1153.
https://doi.org/10.1046/j.1365-2958.2001.02313.x

Germer, J., Becker, G., Metzner, M., Hengge-Aronis, R. 2001. »Role of activator site position and a distal UP-element half-site for sigma factor selectivity at a CRP/H-NS-activated σS-dependent promoter in Escherichia coli.« Molecular Microbiology, 41 (3): 705-716.
https://doi.org/10.1046/j.1365-2958.2001.02548.x

Klauck, E., Lingnau, M., Hengge-Aronis, R. 2001. »Role of the response regulator RssB in sigmaS recognition and initiation of sigmaS proteolysis in Escherichia coli.« Molecular Microbiology, 40 (6): 1381-1390.
https://doi.org/10.1046/j.1365-2958.2001.02482.x

Colland F., Barth M., Hengge-Aronis R., Kolb A. 2000. »sigma factor selectivity of Escherichia coli RNA polymerase: role for CRP, IHF and Lrp transcription factors.« The EMBO Journal, 19 (12): 3028-3037.
https://doi.org/10.1093/emboj/19.12.3028

Hengge-Aronis, R. 2000. »A role for the σ8 subunit of RNA polymerase in the regulation of bacterial virulence.« Advances in Experimental Medicine and Biology, 485: 85.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0034473449&partnerID=40&md5=3de8a594b6102b5f8b765220949ad284

Becker, G., Klauck, E., Hengge-Aronis, R. 1999. »Regulation of RpoS proteolysis in Escherichia coli: The response regulator RssB is a recognition factor that interacts with the turnover element in RpoS.« Proceedings of the National Academy of Sciences, 96 (11): 6439-6444.
https://doi.org/10.1073/pnas.96.11.6439

Biran, I., Klimentiy, L., Hengge-Aronis, R., Ron, E. Z., Rishpon, J. 1999. »On-line monitoring of gene expression.« Microbiology, 145 (8): 2129-2133.
https://doi.org/10.1099/13500872-145-8-2129

Hengge-Aronis, R. 1999. »Interplay of global regulators and cell physiology in the general stress response of Escherichia coli.« Current Opinion in Microbiology, 2 (2): 148-152.
https://doi.org/10.1016/S1369-5274(99)80026-5

Bouché, S., Klauck, E., Fischer, D., Lucassen, M., Jung, K., Hengge-Aronis, R. 1998. »Regulation of RssB-dependent proteolysis in Escherichia coli: a role for acetyl phosphate in a response regulator-controlled process.« Molecular Microbiology, 27 (4): 787-795.
https://doi.org/10.1046/j.1365-2958.1998.00725.x

Bouvier, J., Gordia, S., Kampmann, G., Lange, R., Hengge-Aronis, R., Gutierrez, C. 1998. »Interplay between global regulators of Escherichia coli: effect of RpoS, Lrp and H-NS on transcription of the gene osmC.« Molecular Microbiology, 28 (5): 971-980.
https://doi.org/10.1046/j.1365-2958.1998.00855.x

Fischer, D., Teich, A., Neubauer, P., Hengge-Aronis, R. 1998. »The general stress sigma factor sigmaS of Escherichia coli is induced during diauxic shift from glucose to lactose.« Journal of Bacteriology, 180 (23): 6203-6206.
https://doi.org/10.1128/.180.23.6203-6206.1998

Germer, J., Muffler, A., Hengge-Aronis, R. 1998. »Trehalose is not relevant for in vivo activity of sigmaS-containing RNA polymerase in Escherichia coli.« Journal of Bacteriology, 180 (6): 1603-1606.
https://doi.org/10.1128/jb.180.6.1603-1606.1998

Marschall, C., Labrousse, V., Kreimer, M., Weichart, D., Kolb, A., Hengge-Aronis, R. 1998. »Molecular analysis of the regulation of csiD, a carbon starvation-inducible gene in Escherichia coli that is exclusively dependent on σS and requires activation by cAMP-CRP.« Edited by M. Gottesman. Journal of Molecular Biology, 276 (2): 339-353.
https://doi.org/10.1006/jmbi.1997.1533

Zhang, A., Altuvia, S., Tiwari, A., Argaman, L., Hengge-Aronis, R., Storz, G. 1998. »The OxyS regulatory RNA represses rpoS translation and binds the Hfq (HF-I) protein.« The EMBO Journal, 17 (20): 6061-6068.
https://doi.org/10.1093/emboj/17.20.6061

Beglova, N., Fischer, D., Hengge-Aronis, R., Gehring, K. 1997. »1H, 15N and 13C NMR Assignments, Secondary Structure and Overall Topology of the Escherichia Coll Glgs Protein.« European Journal of Biochemistry, 246 (2): 301-310.
https://doi.org/10.1111/j.1432-1033.1997.t01-1-00301.x

Klauck, E., Böhringer, J., Hengge‐Aronis, R. 1997. »The LysR-like regulator LeuO in Escherichia coli is involved in the translational regulation of rpoS by affecting the expression of the small regulatory DsrA-RNA.« Molecular Microbiology, 25 (3): 559-569.
https://doi.org/10.1046/j.1365-2958.1997.4911852.x

Muffler, A., Barth, M., Marschall, C., Hengge-Aronis, R. 1997. »Heat shock regulation of sigmaS turnover: a role for DnaK and relationship between stress responses mediated by sigmaS and sigma32 in Escherichia coli.« Journal of bacteriology, 179 (2): 445-452.
https://doi.org/10.1128/jb.179.2.445-452.1997

Muffler, A., Traulsen, D. D., Fischer, D., Lange, R., Hengge-Aronis, R. 1997. »The RNA-binding protein HF-I plays a global regulatory role which is largely, but not exclusively, due to its role in expression of the sigmaS subunit of RNA polymerase in Escherichia coli.« Journal of bacteriology, 179 (1): 297-300.
https://doi.org/10.1128/jb.179.1.297-300.1997

Hengge‐Aronis, R. 1996. »Back to log phase: σS as a global regulator in the osmotic control of gene expression in Escherichia coli.« Molecular Microbiology, 21 (5): 887-893.
https://doi.org/10.1046/j.1365-2958.1996.511405.x

Muffler, A., Fischer, D., Altuvia, S., Storz, G., Hengge-Aronis, R. 1996. »The response regulator RssB controls stability of the sigma(S) subunit of RNA polymerase in Escherichia coli.« The EMBO Journal, 15 (6): 1333-1339.
https://doi.org/10.1002/j.1460-2075.1996.tb00475.x

Muffler, A., Fischer, D., Hengge-Aronis, R. 1996. »The RNA-binding protein HF-I, known as a host factor for phage Qbeta RNA replication, is essential for rpoS translation in Escherichia coli.« Genes & Development, 10 (9): 1143-1151.
https://doi.org/10.1101/gad.10.9.1143

Muffler, A., Traulsen, D. D., Lange, R., Hengge-Aronis, R. 1996. »Posttranscriptional osmotic regulation of the sigma(s) subunit of RNA polymerase in Escherichia coli.« Journal of bacteriology, 178 (6): 1607-1613.
https://doi.org/10.1128/jb.178.6.1607-1613.1996

Barth, M., Marschall, C., Muffler, A., Fischer, D., Hengge-Aronis, R. 1995. »Role for the histone-like protein H-NS in growth phase-dependent and osmotic regulation of sigma S and many sigma S-dependent genes in Escherichia coli.« Journal of bacteriology, 177 (12): 3455-3464.
https://doi.org/10.1128/jb.177.12.3455-3464.1995

Böhringer, J., Fischer, D., Mosler, G., Hengge-Aronis, R. 1995. »UDP-glucose is a potential intracellular signal molecule in the control of expression of sigma S and sigma S-dependent genes in Escherichia coli.« Journal of bacteriology, 177 (2): 413-422.
https://doi.org/10.1128/jb.177.2.413-422.1995

Lange, R., Fischer, D., Hengge-Aronis, R. 1995. »Identification of transcriptional start sites and the role of ppGpp in the expression of rpoS, the structural gene for the sigma S subunit of RNA polymerase in Escherichia coli.« Journal of bacteriology, 177 (16): 4676-4680.
https://doi.org/10.1128/jb.177.16.4676-4680.1995

Marschall, C., Hengge-Aronis, R. 1995. »Regulatory characteristics and promoter analysis of csiE, a stationary phase-inducible gene under the control of sigmaS and the cAMP-CRP complex in Escherichia coli.« Molecular Microbiology, 18 (1): 175-184.
https://doi.org/10.1111/j.1365-2958.1995.mmi_18010175.x

Lange, R., Hengge-Aronis, R. 1994. »The cellular concentration of the sigma S subunit of RNA polymerase in Escherichia coli is controlled at the levels of transcription, translation, and protein stability.« Genes & Development, 8 (13): 1600-1612.
https://doi.org/10.1101/gad.8.13.1600

Lange, R., Hengge-Aronis, R. 1994. »The nIpD gene is located in an operon with rpoS on the Escherichia coli chromosome and encodes a novel lipoprotein with a potential function in ceil wall formation.« Molecular Microbiology, 13 (4): 733-743.
https://doi.org/10.1111/j.1365-2958.1994.tb00466.x

Loewen, P. C., Hengge-Aronis, R. 1994. »The Role of the Sigma Factor sigmas (KatF) in Bacterial Global Regulation.« Annual Review of Microbiology. Annual Review of Microbiology, 48 (1): 53-80.
https://doi.org/10.1146/annurev.mi.48.100194.000413

Hengge-Aronis, R., Lange, R., Henneberg, N., Fischer, D. 1993. »Osmotic regulation of rpoS-dependent genes in Escherichia coli.« Journal of Bacteriology, 175 (1): 259-265.
https://doi.org/10.1128/jb.175.1.259-265.1993

Hengge-Aronis, R. 1993. »Survival of hunger and stress: The role of rpoS in early stationary phase gene regulation in E. coli.« Cell, 72 (2): 165-168.
https://doi.org/10.1016/0092-8674(93)90655-A

Lange, R., Barth, M., Hengge-Aronis, R. 1993. »Complex transcriptional control of the sigma s-dependent stationary-phase-induced and osmotically regulated osmY (csi-5) gene suggests novel roles for Lrp, cyclic AMP (cAMP) receptor protein-cAMP complex, and integration host factor in the stationary-phase response of Escherichia coli.« Journal of Bacteriology, 175 (24): 7910-7917.
https://doi.org/10.1128/jb.175.24.7910-7917.1993

Weichart, D., Lange, R., Henneberg, N., Hengge-Aronis, R. 1993. »Identification and characterization of stationary phase inducible genes in Escherichia coli.« Molecular Microbiology, 10 (2): 407-420.
https://doi.org/10.1111/j.1365-2958.1993.tb02672.x

Hengge-Aronis, R., Fischer, D. 1992. »Identification and molecular analysis of glgS, a novel growth-phase-regulated and rpoS-dependent gene involved in glycogen synthesis in Escherichia coli.« Molecular Microbiology, 6 (14): 1877-1886.
https://doi.org/10.1111/j.1365-2958.1992.tb01360.x

Hengge-Aronis, R., Klein, W., Lange, R., Rimmele, M., Boos, W. 1991. »Trehalose synthesis genes are controlled by the putative sigma factor encoded by rpoS and are involved in stationary-phase thermotolerance in Escherichia coli.« Journal of Bacteriology, 173 (24): 7918-7924.
https://doi.org/10.1128/jb.173.24.7918-7924.1991

Lange, R., Hengge-Aronis, R. 1991. »Growth phase-regulated expression of bolA and morphology of stationary-phase Escherichia coli cells are controlled by the novel sigma factor sigma S.« Journal of Bacteriology, 173 (14): 4474-4481.
https://doi.org/10.1128/jb.173.14.4474-4481.1991

Lange, R., Hengge-Aronis, R. 1991. »Identification of a central regulator of stationary-phase gene expression in Escherichia coli.« Molecular Microbiology, 5 (1): 49-59.
https://doi.org/10.1111/j.1365-2958.1991.tb01825.x

Hengge-Aronis, R., Boos, W. 1986. »Translational control of exported proteins in Escherichia coli.« Journal of Bacteriology, 167 (2): 462-466.
https://doi.org/10.1128/jb.167.2.462-466.1986

Hengge, R., Boos, W. 1985. »Defective secretion of maltose- and ribose-binding proteins caused by a truncated periplasmic protein in Escherichia coli.« Journal of Bacteriology, 162 (3): 972.
https://doi.org/10.1128/JB.162.3.972-978.1985

Hengge, R., Boos, W. 1983. »Maltose and lactose transport in Escherichia coli Examples of two different types of concentrative transport systems.« Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 737 (3-4): 443-478.
https://doi.org/10.1016/0304-4157(83)90009-6

Hengge, R., Larson, T., Boos, W. 1983. »sn-Glycerol-3-phosphate transport in Salmonella typhimurium.« Journal of Bacteriology, 155 (1): 186-195.
https://doi.org/10.1128/JB.155.1.186-195.1983

Larson, T., Ludtke, D., Hengge, R., Boos, W. 1982. »sn-Glycerol-3-phosphate transport in Escherichia coli and Salmonella typhimurium.« Tokai Journal of Experimental and Clinical Medicine, 7 Suppl: 149-155.
https://www.scopus.com/inward/record.uri?eid=2-s2.0-0020394503&partnerID=40&md5=7c36119b288d6c972b7b64a6ea378181

Brass, J., Boos, W., Hengge, R. 1981. »Reconstitution of maltose transport in malB mutants of Escherichia coli through calcium-induced disruptions of the outer membrane.« Journal of Bacteriology, 146 (1): 10.
https://doi.org/10.1128/JB.146.1.10-17.1981

Conference Proceedings

Douny, L., Hernández Lobato, J. I., Séré, A., Sawadogo, S., Hengge, R. 2023. »The hunter shirt: the role of Acacia nilotica in fermentative textile dyeing.« Presented at the XXXI International Horticultural Congress (IHC2022): International Symposium on Natural Colorants from Plants. International Society for Horticultural Science (ISHS), 67-76.
https://doi.org/10.17660/ActaHortic.2023.1361.8

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Knowledge Transfer

Research Objects

Hengge, R. 2010. »Science & Theatre Project, in cooperation with English Theatre Berlin/International Performing Arts Centre.«
https://www.etberlin.de/producing-series/science-theatre/

Exhibitions

Beyer, B., De Visscher, E., Hathroubi, S., Hengge, R., Liedtke, M., Mareis C., Miodragovic, N., Rešetar, I., Suárez, D. Bacterial Cellulose: Co-Weaving Biofilms. Exhibition. Installation for the Triennale XXIII: »Unknown Unknows, An Introduction to Mysteries«. Milan. 15 July 2022 - 11 December 2022.
https://www.matters-of-activity.de/de/activities/8617/bacterial-cellulose-co-weaving-biofilms

Douny, L. (curator), Krauthausen, K. (curator), Sattler, F. (curator), Thindi, T. (film installation). DAOULA | sheen. West African Wild Silk on Its Way. Exhibition. In cooperation with Séré, A., Sawadogo, S., Dayo, L., Dayo, H., Fofana, A., Sakira, S., Dao, D., Sanogo, B., Séré, M., Konate, A., Ilboudo, M. in Burkina Faso and Bonavia, E., Buch, S., Dierichs, K., Eder, M., Farmer, J., Hathroubi, S., Hengge, R., Hernández Lobato, J. I., Illing-Günther, H., Hassoune, S., Mählmann, J., Panzer, M. M., Rešetar, I., Rosenthal, N., Santos Thomas, C., Sauer, C., Sermonet, J., Shone, J., Schneider, M., Strauß, W. in Germany. Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin. Tieranatomisches Theater. 17 November 2022 - 29 April 2023.
https://tieranatomisches-theater.de/project/ausstellung-ab-17-november-2022daoula-sheenwest-african-wild-silk-on-its-way/

Contributions to Exhibitions

Sauer, C. (project leader), Miodragović, N. (project leader, designer), Beyer, B. (designer), Rešetar, I. (designer), Suarez, D. (designer, video producer), Singer, N. (designer), Hengge, R. (microbiologist), Hathroubi, S. (microbiologist), Eder, M. (materials scientist), Bidan, C. (materials scientist) »Active Curtain.« Humboldt Labor, Humboldt Forum Berlin. Since 29 April 2021.
https://www.humboldt-labor.de/en/projects/clusters-of-excellence/active-curtain-project

Zheng, B., Hengge, R. et al. »Wanwu Council.« At the exhibition: Wanwu Council. Gropius Bau Berlin. 6 August 2021 - 8 August 2021.
https://www.berlinerfestspiele.de/en/gropiusbau/programm/2021/zheng-bo/wanwu-council.html

Talks & Events

Talks & Presentations

Hengge, R. Large-scale extracellular matrix architecture and tissue-like morphogenesis as emerging properties of bacterial multicellularity. Talk at the DFG-SPP2389 Kick-off Meeting on Emergent Functions of Bacterial Multicellularity, Technische Universität Dresden. 12 January 2023.

Hengge, R. RpoS and beyond: from the general stress response to human-curated plant-microbe interactions in art and design. Talk at the Molecular and Systems Microbiology: a Conference in Honor of Carol Gross, Asilomar-Pacific Grove, CA, USA. 7 July 2023.

Sauer, C. (organizer), Stoll, M. (organizer), Schneider, M. (organizer), Fransén Waldhör, E. (moderator), Fratzl, P. (panelist), Guiducci, L. (panelist), Hengge, R. (panelist), Illing-Günther, H. (panelist), Krauthausen, K. (panelist) Book Launch of "Architectures of Weaving". Transdisciplinary Roundtable Discussion with Editors and Contributors of the Multidisciplinary Anthology "Architectures of Weaving", Architecture Gallery Aedes / Aedes Metropolitan Laboratory, Berlin. 25 January 2023.
https://www.matters-of-activity.de/en/activities/9582/?preview

Hengge, R., Schäffner, W. »Active Curtain Project«. Long Night of the Sciences, »Meet the Scientist«, Humboldt Laboratory, Berlin. 2 July 2022.

Hengge, R. C-di-GMP signaling in bacterial multicellularity. Talk at the EMBO Conference on Bacterial Networks (Bacnet22), European Molecular Biology Organization, Sant Feliu. 5 September 2022.

Hengge, R. Linking bacterial growth, survival and multicellularity with second messengers as triggers and drivers. Talk at the DFG-SPP1879 International Symposium on ‘Nucleotide Second Messenger Signaling in Bacteria‘, Harnack-Haus, Berlin. 23 May 2022.

Hengge, R. Linking bacterial growth, survival and multicellularity with second messengers as triggers and drivers. Talk at the International Workshop on the Interdisciplinary Life of Microbes: from Single Cells to Multicellular Aggregates, Max Planck Institute for the Physics of Complex Systems, Dresden. 7 November 2022.

Hengge, R. Multicellularity as an emergent property of life: spatial organization of molecular signaling and gene expression in bacterial biofilms. Talk at the Invited lecture series of the Institute of Plant Physiology and Microbiology, Universität Zürich. 6 June 2022.

Hengge, R. Principles of high-specificity global and local c-di-GMP signaling. Talk at the Annual Conference of the Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM), Düsseldorf. Virtual. 21 February 2022.

Beyer, B., Cubasch, A., Fratzl, P., Hengge, R., Mareis, C., Perraudin, L., Sauer, C., Schäffner, W., for the Cluster of Excellence »Matters of Activity«. Can Bacteria Spin a Yarn? We Need a New Culture of Materials. Panel Presentation at the »Can Bacteria Spin a Yarn? We Need a New Culture of Materials«, Humboldt Forum Berlin. Hybrid. 29 April 2021.
https://www.humboldtforum.org/en/programm/termin/science-humanities/do-bacteria-spin-a-yarn-20472/

Hengge, R., Krauthausen, K. The Event of a Fibre. Talk at the »Architectures of Weaving«, Session 2. Symposium organized by the project Weaving, Sauer, C., Stoll, M.; Beyer, B. et al. Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin, weißensee school of art and design berlin. Virtual. 2 July 2021.
https://www.matters-of-activity.de/en/activities/5540/architectures-of-weaving

Hengge, R. Multicellularity as an emergent property of life: Spatial organization of gene expression and c-di-GMP signaling in Escherichia coli biofilms. Talk at the Lecture Series at Wissenschaftskolleg Greifswald, Wissenschaftskolleg, Greifswald. Virtual. 7 June 2021.

Hengge, R. Multicellularity as an emergent property of life: spatial organization of molecular signaling and gene expression in bacterial biofilms. Talk at the Wissenschaftskolleg Greifswald. Virtual. 7 June 2021.

Hengge, R. Principles of high-specificity local and global c-di-GMP signaling. Talk at the DFG-SPP1879 Progress Meeting on 'Nucleotide Second Messenger Signaling in Bacteria', Berlin. Virtual. 20 May 2021.

Hengge, R. Spatialization of living systems across the scales. Talk at the Activity II: Space and Materiality. Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin. 19 March 2021.

Hengge, R. Spatialization of living systems across the scales. Talk at the the Conference 'Activity II: Space and Materiality' of the Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin. Virtual. 19 March 2021.

Evans, M., Hengge, R. Buckling, Wrinkling and Folding: Microstructure, Active Matter Behaviour and Geometric Modelling of Bacterial Biofilms. Talk at the 1st Annual Conference »The Analog in the Digital Age«. Virtual. 11 November 2020.
https://www.virtualspace.matters-of-activity.de/annualconference/?id=11

Hathroubi, S. (contributor), Beyer, B. (contributor), Rešetar, I. (contributor), Hengge, R. (organiser). Collaborative research with bacterial cellulose. Talk at the Seminar at Hengge Lab, Faculty of Biology - Department of Microbiology, Humboldt-Universität zu Berlin. Virtual. 13 July 2020.

Hengge, R. Bacterial biofilms: Linking bacterial growth, survival and multicellularity with second messengers as triggers and drivers. Keynote at the the 5th Microbial Stress Meeting of the European Federation of Biotechnology (EFB), Rome, Italy. Virtual. 18 November 2020.

Hengge, R. Bacterial biofilms: Linking bacterial growth, survival and multicellularity with second messengers as triggers and drivers. Keynote at the the Annual Conference of the Belgian Society for Microbiology, Brussels, Belgium. Virtual. 16 October 2020.

Hengge, R. Bacterial biofilms: Linking bacterial growth, survival and multicellularity with second messengers as triggers and drivers. Talk at the the Biofilms 9 Conference, Karlsruhe. Virtual. 1 October 2020.

Hengge, R. Signal input into the E. coli biofilm matrix control network via DgcE and a GTPase partner system. Talk at the the SPP1879 Progress Meeting on 'Nucleotide Second Messenger Signaling in Bacteria', Göttingen. 28 February 2020.

Hengge, R. A c-di-GMP-based switch controls local heterogeneity of extracellular matrix synthesis which is crucial for architecture, integrity and morphogenesis of E. coli macrocolony biofilms. Talk at the the International DFG-SPP1617 Symposium on Phenotypic Heterogeneity and Sociobiology of Bacterial Populations, Schloss Hohenkammer, Munich. 29 March 2019.

Hengge, R. c-di-GMP signaling in building the extracellular matrix architecture of E. coli biofilms. Talk at the the EMBO-EMBL Symposium on Novel Approaches and Concepts in Microbiology, Heidelberg, Germany. 14 July 2019.

Hengge, R. How billions of bacteria cooperate to generate a functional 3D biofilm matrix architecture at a scale much larger than the cells that build it. Talk at the the 2. International Conference on Bacterial Morphogenesis, Survival and Virulence, Monkey Valley Resort, Cape Town, South Africa. 26 November 2019.

Hengge, R. Signal input into the E. coli biofilm matrix control network via DgcE and a GTPase partner system. Talk at the the EMBO Conference on Bacterial Networks, Sant Feliu de Guixols, Spain. 2 September 2019.

Hengge, R. Spatial organization of transcriptional control and c-di-GMP signaling in Escherichia coli biofilms. Keynote at the the Annual Meeting of the Israeli Society of Microbiology, Rehovot, Israel. 6 March 2019.

Events & Workshops

Quinz, E., Ribault, P. (moderators), Saraceno, T. (co-organizer), Chiaramonte, X., Hengge, R., Jäger, P., Jarry, A., Jordan, A., Müller, M. (guests). »Dissect« – An artistic research on a more equal balance of human- techno- and biodiversity. Discussion about Tomás Saraceno's Spiders. Tieranatomisches Theater, Humboldt-Universität zu Berlin. Chaire Arts & Sciences of the École polytechnique, Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin, École nationale supérieure des Arts Décoratifs (EnsAD), Fondation Daniel et Nina Carasso, Tieranatomisches Theater, Humboldt-Universität zu Berlin. 4 November 2022.
https://berlinscienceweek.com/de/event/dissect-2/

Zheng, B., Hengge, R., Laitinen, R., Rillig, M. Botanical Comrades 植物同志 Plants Practice Politics. Gropius Bau, Berlin. In cooperation with Schering Stiftung. Schering Stiftung. Hybrid. 7 November 2020.
https://falling-walls.com/event/botanical-comrades-植物同志-plants-practice-politics/

Cegelski, L. (Lecturer), Hengge, R., Krauthausen, K. (Organizers) Weaving in Different Disciplines: Structure and properties of the polymer fibers of the biofilm matrix of E. coli. Cluster of Excellence »Matters of Activity«, Humboldt-Universität zu Berlin. 30 August 2019.

Teaching & Supervision

Teaching & Courses

Sauer, C., Guiducci, L., Razghandi, K., Fransén Waldhör, E., Schneider, M., Scaling Nature (1) – Wrinkles. MoA Design Research Studio, With contributions by Kycia, A., Bidan, C., Fratzl, P., Friedman, M., Hengge, R. and Stoll, M.. Student projects from Scaling Nature (1) were presented at NuThinkers during Domotex Tradefair in Hanover, 10-13 January 2020. weißensee school of art and design berlin. 15 April 2019 - 20 July 2019.
https://www.matters-of-activity.de/en/activities/1130/moa-design-studio-scaling-nature-1-wrinkles

Awards & Funding

Prizes & Competition Awards

Hengge, R. 1998. Gottfried Wilhelm Leibniz Prize. Gottfried Wilhelm Leibniz Prize. Deutsche Forschungsgemeinschaft (DFG).

Hengge, R. 1996. Research Award (Landesforschungspreis) of the State of Baden-Württemberg. Land Baden-Württemberg.

Hengge, R. 1993. Young-Investigator Award of the DGHM. Deutsche Gesellschaft für Hygiene und Mikrobiologie.

External Grants, Fellowships, Scholarships & Residencies

Hengge, R. 2009. ERC Advanced Researcher Grant. ERC, Project funding.

Hengge, R. 1995. Dozenten-Stipendium of the Fonds der Chemischen Industrie. Fonds der Chemischen Industrie Fellowship.

Networks

Cooperations

Hengge, R. (Scientific Coordinator) 2016 - 2022. DFG Priority Programme "Nucleotide Second Messenger Signaling in Bacteria" (SPP1879).
https://www.spp1879.de

Hengge, R. (Scientific Coordinator) 2002 - 2008. DFG Priority Programme "Proteolysis in Prokaryotes: Protein Quality Control and Regulatory Principle" (SPP1132).
https://gepris.dfg.de/gepris/projekt/5471531?language=en

Review Activities & Expertises

Hengge, R. Since 2013. LOEWE Centre for Synthetic Biology (SynMikro), Scientific Advisory Board. Universität Marburg, Marburg.

Hengge, R. Since 2011. Robert-Koch Stiftung, Scientific Advisory Council. Robert-Koch Stiftung, Berlin.

Editorial Works

Hengge, R. Since 2020. Current Research in Microbiology Editorial Board. Current Research in Microbiology.

Hengge, R. Since 2020. Trends in Microbiology Editorial Board. Trends in Microbiology.

Hengge, R. Since 2016. Current Opinion on Microbiology Editorial Board. Current Opinion on Microbiology.

Hengge, R. Since 2005. EMBO Journal Editorial Board. EMBO Journal.

Hengge, R. Since 2005. EMBO Reports Editorial Board. EMBO Reports.

Memberships

Hengge, R. Since 2015. Hermann von Helmholtz Center for Cultural Techniques (HZK). Member.

Hengge, R. Since 2012. American Academy of Microbiology. Elected Membership.

Hengge, R. Since 2009. European Academy of Microbiology. Founding Member and Member of the Executive Board.

Hengge, R. Since 2004. European Organization of Molecular Biology. Elected Membership.

Hengge, R. Since 2001. Deutsche Akademie der Naturforscher Leopoldina. Elected Membership.

Hengge, R. Since 2000. Berlin-Brandenburg Academy of Sciences and Humanities. Elected Membership.

Media Contributions

Contributions in TV & Radio

Hengge, R. Bakterien - Gefahr im Biofilm. Radio contribution, Bayern 2. 21 minutes, 12 August 2021.
https://www.br.de/mediathek/podcast/radiowissen/488