What is the Association Between White Brain Matter Tract Density and Patients’ Overall Survival with an Aggressive Brain Tumor (Glioblastoma)?
Image of the cortical ends of the white matter of the human brain, created in the »Matters of Activity« Cluster of Excellence. Copyright: MoA/Lucius Fekonja
In this prognostic study of 112 patients and 70 patients with glioblastoma, published in JAMA Neurology, a newly developed white matter tract density index (TDI) was significantly associated with overall survival in glioblastoma. The TDI had a stronger correlation and survival prediction than other commonly used prognostic factors. The TDI appears to be a reliable predictor of patient outcomes; given these findings, this index may be considered in future clinical trials and potentially incorporated into clinical practice.
Find the complete publication here:
https://jamanetwork.com/journals/jamaneurology/article-abstract/2809862