Prof. Dr. rer. nat. Ingolf Sack
Ingolf Sack is an expert in NMR spectroscopy, MRI, biomechanics, acoustics and tumor mechanics. He conducts interdisciplinary research and development in the field of elastography. He is a pioneer in imaging mechanical soft tissue properties such as stiffness and viscosity of living tissue for clinical diagnosis and basic research.
In 2010, he became a Heisenberg Professor of Elastography of the German Research Foundation. Since 2019 he is a full professor for quantitative MRI and elastography at the Department of Radiology, Charité - Universitätsmedizin Berlin.
Charité - Universitätsmedizin Berlin
Klinik für Radiologie (mit dem Bereich Kinderradiologie) (CCM)
Charitéplatz 1
10117 Berlin
Articles
Li, D., Loneker, A. E., Safraou, Y., Ford, J., Mihelc, E., Sakane, S., Kisseleva, T., Levental, K. R., Levental, I., Sack, I., Janmey, P. A., Wells, R. G. 2026. »Cholesterol-containing lipid crystals can directly stiffen the rat steatotic liver before fibrosis.« Proceedings of the National Academy of Sciences, 123 (2): e2518060123.
https://doi.org/10.1073/pnas.2518060123
Garcia, S. R. M., Oppenheimer, J., Meyer, T., Friedersdorff, F., Sack, I. 2025. »Association of In Vivo Kidney Stiffness Measured by Multifrequency MR Elastography and Long‐Term Renal Function in Transplant Recipients and Living Donors.« Journal of Magnetic Resonance Imaging, 62 (3): 792-799.
https://doi.org/10.1002/jmri.29799
Bergs, J., Morr, A. S., Silva, R. V., Infante‐Duarte, C., Sack, I. 2024. »The Networking Brain: How Extracellular Matrix, Cellular Networks, and Vasculature Shape the In Vivo Mechanical Properties of the Brain.« Advanced Science, 11 (31): 2402338.
https://doi.org/10.1002/advs.202402338
Sack, I. 2022. »Magnetic resonance elastography from fundamental soft-tissue mechanics to diagnostic imaging.« Nature Reviews Physics, 5 (1): 25-42.
https://doi.org/10.1038/s42254-022-00543-2
Snellings, J., Keshi, E., Tang, P., Daneshgar, A., Willma, E. C., Haderer, L., Klein, O., Krenzien, F., Malinka, T., Asbach, P., Pratschke, J., Sauer, I. M., Braun, J., Sack, I., Hillebrandt, K. 2022. »Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues.« Biomaterials Advances, 139: 212999.
https://doi.org/10.1016/j.bioadv.2022.212999
Everwien, H., Ariza de Schellenberger, A., Haep, N., Tzschätzsch, H., Pratschke, J., Sauer, I. M., Braun, J., Hillebrandt, K. H., Sack, I. 2020. »Magnetic resonance elastography quantification of the solid-to-fluid transition of liver tissue due to decellularization.« Journal of the Mechanical Behavior of Biomedical Materials, 104: 103640.
https://doi.org/10.1016/j.jmbbm.2020.103640