Prof. Dr. med. Igor M. Sauer

Articles in Edited Volumes

Raschzok, N., Teichgräber, U., Pratschke, J., Sauer, I. M. 2016. »Preclinical Swine Models for Monitoring of Hepatocyte Transplantation by MRI.« Springer New York, 201-214.
https://doi.org/10.1007/978-1-4939-6506-9_14

Articles

Alves, J. M., Prado-López, S., Tomás, L., Valecha, M., Estévez-Gómez, N., Alvariño, P., Geisel, D., Modest, D. P., Sauer, I. M., Pratschke, J., Raschzok, N., Sers, C., Mamlouk, S., Posada, D. 2022. »Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing.« Cancer Letters, 543: 215767.
https://doi.org/10.1016/j.canlet.2022.215767

Felsenstein, M., Lindhammer, F., Feist, M., Hillebrandt, K. H., Timmermann, L., Benzing, C., Globke, B., Zocholl, D., Hu, M., Fehrenbach, U., Sinn, B. V., Pelzer, U., Sauer, I. M., Pratschke, J., Malinka, T. 2022. »Perineural Invasion in Pancreatic Ductal Adenocarcinoma (PDAC): A Saboteur of Curative Intended Therapies?« Journal of Clinical Medicine, 11 (9): 2367.
https://doi.org/10.3390/jcm11092367

Hillebrandt, K. H., Moosburner, S., Winter, A., Nevermann, N., Raschzok, N., Malinka, T., Sauer, I. M., Schmelzle, M., Pratschke, J., Chopra, S. 2022. »The influence of the COVID-19 pandemic on surgical therapy and care: a cross-sectional study.« BMC Surgery, 22 (1)
https://doi.org/10.1186/s12893-022-01708-7

Muth, V., Gassner, J. M., Moosburner, S., Lurje, G., Michelotto, J., Strobl, F., Knaub, K., Engelmann, C., Tacke, F., Selzner, M., Pratschke, J., Sauer, I. M., Raschzok, N. 2022. »Ex Vivo Liver Machine Perfusion: Comprehensive Review of Common Animal Models.« Tissue Engineering Part B: Reviews. ahead of print.
https://doi.org/10.1089/ten.TEB.2022.0018

Pavicevic, S., Reichelt, S., Uluk, D., Lurje, I., Engelmann, C., Modest, D. P., Pelzer, U., Krenzien, F., Raschzok, N., Benzing, C., Sauer, I. M., Stintzing, S., Tacke, F., Schöning, W., Schmelzle, M., Pratschke, J., Lurje, G. 2022. »Prognostic and Predictive Molecular Markers in Cholangiocarcinoma.« Cancers, 14 (4): 1026.
https://doi.org/10.3390/cancers14041026

Queisner, M., Pogorzhelskiy, M., Remde, C., Pratschke, J., Sauer, I. M. 2022. »VolumetricOR: A New Approach to Simulate Surgical Interventions in Virtual Reality for Training and Education.« Surgical Innovation, 29 (3): 406-415.
https://doi.org/10.1177/15533506211054240

Raschzok, N., Stintzing, S., Heinemann, V., Rauch, G., Ricke, J., Guckenberger, M., Kurreck, A., Alig, A. H. S., Stahler, A., Bullinger, L., Schmelzle, M., Schöning, W., Lurje, G., Krenzien, F., Haase, O., Rau, B., Gebauer, B., Sauer, I. M., Pratschke, J., Modest, D. P. 2022. »FIRE-9 – PORT / AIO-KRK-0418: a prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of adjuvant/additive chemotherapy in patients with definitely-treated metastatic colorectal cancer.« BMC Cancer, 22 (1)
https://doi.org/10.1186/s12885-022-09422-6

Snellings, J., Keshi, E., Tang, P., Daneshgar, A., Willma, E. C., Haderer, L., Klein, O., Krenzien, F., Malinka, T., Asbach, P., Pratschke, J., Sauer, I. M., Braun, J., Sack, I., Hillebrandt, K. 2022. »Solid fraction determines stiffness and viscosity in decellularized pancreatic tissues.« Biomaterials Advances, 139: 212999.
https://doi.org/10.1016/j.bioadv.2022.212999

Borlak, F., Reutzel-Selke, A., Schirmeier, A., Gogolok, J., von Hoerschelmann, E., Sauer, I. M., Pratschke, J., Bahra, M., Schmuck, R. B. 2021. »Notch Signaling Pathway in Pancreatobiliary Tumors.« Medicina, 57 (2): 105.
https://doi.org/10.3390/medicina57020105

Gül-Klein, S., Hegermann, H., Röhle, R., Schmelzle, M., Tacke, F., Schöning, W., Öllinger, R., Dziodzio, T., Maier, P., Plewe, J., Horst, D., Sauer, I. M., Pratschke, J., Lachmann, N., Eurich, D. 2021. »Donor-Specific Antibodies Against Donor Human Leukocyte Antigen are Associated with Graft Inflammation but Not with Fibrosis Long-Term After Liver Transplantation: An Analysis of Protocol Biopsies.« Journal of Inflammation Research, Volume 14: 2697-2712.
https://doi.org/10.2147/JIR.S307778

Keshi, E., Tang, P., Weinhart, M., Everwien, H., Moosburner, S., Seiffert, N., Lommel, M., Kertzscher, U., Globke, B., Reutzel-Selke, A., Strücker, B., Pratschke, J., Sauer, I. M., Haep, N., Hillebrandt, K. H. 2021. »Surface modification of decellularized bovine carotid arteries with human vascular cells significantly reduces their thrombogenicity.« Journal of Biological Engineering, 15 (1)
https://doi.org/10.1186/s13036-021-00277-2

Moosburner, S., Gassner, J. M., Pratschke, J., Sauer, I. M., Raschzok, N. 2021. »Smartphone Apps to Stratify the Risk of Early Allograft Failure Are Just the Beginning for Next‐Generation Outcome Prediction in Transplantation Medicine.« Hepatology Communications, 6 (1): 249.
https://doi.org/10.1002/hep4.1755

Pfitzner, B., Chromik, J., Brabender, R., Fischer, E., Kromer, A., Winter, A., Moosburner, S., Sauer, I. M., Malinka, T., Pratschke, J., Arnrich, B., Maurer, M. M. 2021. »Perioperative Risk Assessment in Pancreatic Surgery Using Machine Learning.« Annual International Conference of the IEEE Engineering in Medicine & Biology Society, 2021 (Nov): 2211-2214.
https://doi.org/10.1109/EMBC46164.2021.9630897

Picht, T., Calvé, M. L., Tomasello, R., Fekonja, L., Gholami, M. F., Bruhn, M., Zwick, C., Rabe, J. P., Müller-Birn, C., Vajkoczy, P., Sauer, I. M., Zachow, S., Nyakatura, J. A., Ribault, P., Pulvermüller, F. 2021. »Letter: A Note on Neurosurgical Resection and Why We Need to Rethink Cutting.« Neurosurgery. E289–E291.
https://doi.org/10.1093/neuros/nyab326

Schmuck, R. B., Lippens, E., Wulsten, D., Garske, D. S., Strönisch, A., Pratschke, J., Sauer, I. M., Duda, G. N., Bahra, M., Cipitria, A. 2021. »Role of extracellular matrix structural components and tissue mechanics in the development of postoperative pancreatic fistula.« Journal of Biomechanics, 128: 110714.
https://doi.org/10.1016/j.jbiomech.2021.110714

Seiffert, N., Tang, P., Keshi, E., Reutzel-Selke, A., Moosburner, S., Everwien, H., Wulsten, D., Napierala, H., Pratschke, J., Sauer, I. M., Hillebrandt, K. H., Struecker, B. 2021. »In vitro recellularization of decellularized bovine carotid arteries using human endothelial colony forming cells.« Journal of Biological Engineering, 15 (1)
https://doi.org/10.1186/s13036-021-00266-5

Von Hoerschelmann, E., Neumann, C. C. M., Felsenstein, M., Gogolok, J., Reutzel-Selke, A., Sauer, I. M., Pratschke, J., Bahra, M., Schmuck, R. B. 2021. »Cancer Associated Fibroblasts Derived from Pancreatic Adenocarcinoma and Their Role in Cell Migration.« Anticancer Research, 41 (9): 4229-4238.
https://doi.org/10.21873/anticanres.15227

Winter, A., Maurer, M. M., Schmelzle, M., Malinka, T., Biebl, M., Fikatas, P., Kröll, D., Sauer, I. M., Hippler-Benscheidt, M., Pratschke, J., Chopra, S. 2021. »Digitale Komplikationserfassung in der Viszeralchirurgie: Möglichkeiten und Evaluation eines Instrumentes für das Qualitätsmanagement.« Der Chirurg, 93 (4): 381-387.
https://doi.org/10.1007/s00104-021-01482-x

Winter, A., Maurer, M. M., Schmelzle, M., Malinka, T., Biebl, M., Fikatas, P., Kröll, D., Sauer, I. M., Hippler-Benscheidt, M., Pratschke, J., Chopra, S. 2021. »Digitale Komplikationserfassung in der Viszeralchirurgie: Möglichkeiten und Evaluation eines Instrumentes für das Qualitätsmanagement.« Der Chirurg.
https://doi.org/10.1007/s00104-021-01482-x

Claussen, F., Gassner, J. M. G. V., Moosburner, S., Wyrwal, D., Nösser, M., Tang, P., Wegener, L., Pohl, J., Reutzel-Selke, A., Arsenic, R., Pratschke, J., Sauer, I. M., Raschzok, N. 2020. »Dual versus single vessel normothermic ex vivo perfusion of rat liver grafts using metamizole for vasodilatation.« PLOS ONE, 15 (7): e0235635.
https://doi.org/10.1371/journal.pone.0235635

Czigany, Z., Lurje, I., Schmelzle, M., Schöning, W., Öllinger, R., Raschzok, N., Sauer, I. M., Tacke, F., Strnad, P., Trautwein, C., Neumann, U. P., Fronek, J., Mehrabi, A., Pratschke, J., Schlegel, A., Lurje, G. 2020. »Ischemia-Reperfusion Injury in Marginal Liver Grafts and the Role of Hypothermic Machine Perfusion: Molecular Mechanisms and Clinical Implications.« Journal of Clinical Medicine, 9 (3): 846.
https://doi.org/10.3390/jcm9030846

Daneshgar, A., Klein, O., Nebrich, G., Weinhart, M., Tang, P., Arnold, A., Ullah, I., Pohl, J., Moosburner, S., Raschzok, N., Strücker, B., Bahra, M., Pratschke, J., Sauer, I. M., Hillebrandt, K. H. 2020. »The human liver matrisome – Proteomic analysis of native and fibrotic human liver extracellular matrices for organ engineering approaches.« Biomaterials, 257: 120247.
https://doi.org/10.1016/j.biomaterials.2020.120247

Everwien, H., Ariza de Schellenberger, A., Haep, N., Tzschätzsch, H., Pratschke, J., Sauer, I. M., Braun, J., Hillebrandt, K. H., Sack, I. 2020. »Magnetic resonance elastography quantification of the solid-to-fluid transition of liver tissue due to decellularization.« Journal of the Mechanical Behavior of Biomedical Materials, 104: 103640.
https://doi.org/10.1016/j.jmbbm.2020.103640

Everwien, H., Keshi, E., Hillebrandt, K. H., Ludwig, B., Weinhart, M., Tang, P., Beierle, A. S., Napierala, H., Gassner, J. M., Seiffert, N., Moosburner, S., Geisel, D., Reutzel-Selke, A., Strücker, B., Pratschke, J., Haep, N., Sauer, I. M. 2020. »Engineering an endothelialized, endocrine Neo-Pancreas: Evaluation of islet functionality in an ex vivo model.« Acta Biomaterialia, 117: 213-225.
https://doi.org/10.1016/j.actbio.2020.09.022

Gogolok, J., Seidel, E., Strönisch, A., Reutzel-Selke, A., Sauer, I. M., Pratschke, J., Bahra, M., Schmuck, R. B. 2020. »Characterization of Pancreatic and Biliary Cancer Stem Cells in Patient-derived Tissue.« Anticancer Research, 40 (3): 1267-1275.
https://doi.org/10.21873/anticanres.14068

Michelotto, J., Gassner, J. M. G. V., Moosburner, S., Muth, V., Patel, M. S., Selzner, M., Pratschke, J., Sauer, I. M., Raschzok, N. 2020. »Ex vivo machine perfusion: current applications and future directions in liver transplantation.« Langenbeck's Archives of Surgery, 406 (1): 39-54.
https://doi.org/10.1007/s00423-020-02014-7

Michelotto, J., Gassner, J. M. G. V., Moosburner, S., Muth, V., Patel, M. S., Selzner, M., Pratschke, J., Sauer, I. M., Raschzok, N. 2020. »Ex vivo machine perfusion: current applications and future directions in liver transplantation.« Langenbeck's Archives of Surgery.
https://doi.org/10.1007/s00423-020-02014-7

Moosburner, S., Raschzok, N., Schleicher, C., Bösebeck, D., Gaßner, J. M., Ritschl, P. V., Rahmel, A., Sauer, I. M., Pratschke, J. 2020. »Nicht transplantierte Spenderorgane – eine bundesweite Auswertung aller Organangebote für die Lebertransplantation von 2010 bis 2018.« Zeitschrift für Gastroenterologie, 58 (10): 945-954.
https://doi.org/10.1055/a-1199-7432

Moosburner, S., Sauer, I. M., Förster, F., Winklmann, T., Gassner, J. M. G. V., Ritschl, P. V., Öllinger, R., Pratschke, J., Raschzok, N. 2020. »Early Allograft Dysfunction Increases Hospital Associated Costs After Liver Transplantation—A Propensity Score–Matched Analysis.« Hepatology Communications, 5 (3): 526-537.
https://doi.org/10.1002/hep4.1651

Nevermann, N. F., Hillebrandt, K. H., Knitter, S., Ritschl, P. V., Krenzien, F., Benzing, C., Bahra, M., Biebl, M., Sauer, I. M., Öllinger, R., Schöning, W., Schmelzle, M., Pratschke, J. 2020. »COVID-19 pandemic: implications on the surgical treatment of gastrointestinal and hepatopancreatobiliary tumours in Europe.« British Journal of Surgery, 107 (9): e301-e302.
https://doi.org/10.1002/bjs.11751

Nösser, M., Gassner, J. M. G. V., Moosburner, S., Wyrwal, D., Claussen, F., Hillebrandt, K. H., Horner, R., Tang, P., Reutzel-Selke, A., Polenz, D., Arsenic, R., Pratschke, J., Sauer, I. M., Raschzok, N. 2020. »Development of a Rat Liver Machine Perfusion System for Normothermic and Subnormothermic Conditions.« Tissue Engineering Part A, 26 (1-2): 57-65.
https://doi.org/10.1089/ten.TEA.2019.0152

Pohl, J. M. O., Raschzok, N., Eurich, D., Pflüger, M., Wiering, L., Daneshgar, A., Dziodzio, T., Jara, M., Globke, B., Sauer, I. M., Biebl, M., Lurje, G., Schöning, W., Schmelzle, M., Tacke, F., Pratschke, J., Ritschl, P. V., Öllinger, R. 2020. »Outcomes of Liver Resections after Liver Transplantation at a High-Volume Hepatobiliary Center.« Journal of Clinical Medicine, 9 (11): 3685.
https://doi.org/10.3390/jcm9113685

Pohl, J. M. O., Raschzok, N., Eurich, D., Pflüger, M., Wiering, L., Daneshgar, A., Dziodzio, T., Jara, M., Globke, B., Sauer, I. M., Biebl, M., Lurje, G., Schöning, W., Schmelzle, M., Tacke, F., Pratschke, J., Ritschl, P. V., Öllinger, R. 2020. »Outcomes of Liver Resections after Liver Transplantation at a High-Volume Hepatobiliary Center.« Journal of Clinical Medicine, 9 (11): 3685.
https://doi.org/10.3390/jcm9113685

Ritschl, P. V., Wiering, L., Dziodzio, T., Jara, M., Kruppa, J., Schoeneberg, U., Raschzok, N., Butz, F., Globke, B., Seika, P., Maurer, M., Biebl, M., Schöning, W., Schmelzle, M., Sauer, I. M., Tacke, F., Öllinger, R., Pratschke, J. 2020. »The Effects of MELD-Based Liver Allocation on Patient Survival and Waiting List Mortality in a Country with a Low Donation Rate.« Journal of Clinical Medicine, 9 (6): 1929.
https://doi.org/10.3390/jcm9061929

Rüger, C., Feufel, M. A., Moosburner, S., Özbek, C., Pratschke, J., Sauer, I. M. 2020. »Ultrasound in augmented reality: a mixed-methods evaluation of head-mounted displays in image-guided interventions.« International Journal of Computer Assisted Radiology and Surgery, 15 (11): 1895-1905.
https://doi.org/10.1007/s11548-020-02236-6

Rüger, C., Moosburner, S., Sauer, I. M. 2020. »Extended-Reality-Technologien zur Unterstützung chirurgischen Handelns.« Der Chirurg, 91 (7): 544-552.
https://doi.org/10.1007/s00104-020-01188-6

Wiering, L., Sponholz, F., Brandl, A., Dziodzio, T., Jara, M., Dargie, R., Eurich, D., Schmelzle, M., Sauer, I. M., Aigner, F., Kotsch, K., Pratschke, J., Öllinger, R., Ritschl, P. V. 2020. »Perioperative Pleural Drainage in Liver Transplantation: A Retrospective Analysis from a High-Volume Liver Transplant Center.« Annals of Transplantation, 25
https://doi.org/10.12659/AOT.918456

Wiering, L., Öllinger, R., Kruppa, J., Schoeneberg, U., Dziodzio, T., Jara, M., Biebl, M., Dargie, R., Raschzok, N., Schöning, W., Eurich, D., Schmelzle, M., Sauer, I. M., Pratschke, J., Ritschl, P. V. 2020. »Hospitalization Before Liver Transplantation Predicts Posttransplant Patient Survival: A Propensity Score–Matched Analysis.« Liver Transplantation, 26 (5): 628-639.
https://doi.org/10.1002/lt.25748

Albrecht, J., Polenz, D., Kühl, A. A., Rogasch, J. M. M., Leder, A., Sauer, I. M., Babos, M., Mócsai, G., Beindorff, N., Steffen, I. G., Brenner, W., Koziolek, E. J. 2019. »Diffusion-weighted magnetic resonance imaging using a preclinical 1 T PET/MRI in healthy and tumor-bearing rats.« EJNMMI Research, 9 (1)
https://doi.org/10.1186/s13550-019-0489-6

Daneshgar, A., Tang, P., Remde, C., Lommel, M., Moosburner, S., Kertzscher, U., Klein, O., Weinhart, M., Pratschke, J., Sauer, I. M., Hillebrandt, K. H. 2019. »Teburu—Open source 3D printable bioreactor for tissue slices as dynamic three‐dimensional cell culture models.« Artificial Organs, 43 (10): 1035-1041.
https://doi.org/10.1111/aor.13518

Felgendreff, P., Raschzok, N., Kunze, K., Leder, A., Lippert, S., Klunk, S., Tautenhahn, H., Hau, H., Schmuck, R. B., Reutzel-Selke, A., Sauer, I. M., Bartels, M., Morgül, M. H. 2019. »Tissue-based miRNA mapping in alcoholic liver cirrhosis: different profiles in cirrhosis with or without hepatocellular carcinoma.« Biomarkers, 25 (1): 62-68.
https://doi.org/10.1080/1354750X.2019.1691267

Gassner, J. M. G. V., Nösser, M., Moosburner, S., Horner, R., Tang, P., Wegener, L., Wyrwal, D., Claussen, F., Arsenic, R., Pratschke, J., Sauer, I. M., Raschzok, N. 2019. »Improvement of Normothermic Ex Vivo Machine Perfusion of Rat Liver Grafts by Dialysis and Kupffer Cell Inhibition With Glycine.« Liver Transplantation, 25 (2): 275-287.
https://doi.org/10.1002/lt.25360

Hillebrandt, K. H., Everwien, H., Haep, N., Keshi, E., Pratschke, J., Sauer, I. M. 2019. »Strategies based on organ decellularization and recellularization.« Transplant International.
https://doi.org/10.1111/tri.13462

Horner, R., Gassner, J. G. M. V., Kluge, M., Tang, P., Lippert, S., Hillebrandt, K. H., Moosburner, S., Reutzel-Selke, A., Pratschke, J., Sauer, I. M., Raschzok, N. 2019. »Impact of Percoll purification on isolation of primary human hepatocytes.« Scientific Reports, 9 (1)
https://doi.org/10.1038/s41598-019-43042-8

Iske, J., Nian, Y., Maenosono, R., Maurer, M., Sauer, I. M., Tullius, S. G. 2019. »Composite tissue allotransplantation: opportunities and challenges.« Cellular & Molecular Immunology, 16 (4): 343-349.
https://doi.org/10.1038/s41423-019-0215-3

Krenzien, F., Keshi, E., Splith, K., Griesel, S., Kamali, K., Sauer, I. M., Feldbrügge, L., Pratschke, J., Leder, A., Schmelzle, M. 2019. »Diagnostic Biomarkers to Diagnose Acute Allograft Rejection After Liver Transplantation: Systematic Review and Meta-Analysis of Diagnostic Accuracy Studies.« Frontiers in Immunology, 10
https://doi.org/10.3389/fimmu.2019.00758

Maurer, M. M., Sauer, I. M., Pratschke, J., Tullius, S. G. 2019. »First Healthy Baby After Deceased Donor Uterus Transplantation.« Birth to a New Era? Transplantation, 103 (4): 652-653.
https://doi.org/10.1097/TP.0000000000002627

Moosburner, S., Remde, C., Tang, P., Queisner, M., Haep, N., Pratschke, J., Sauer, I. M. 2019. »Real world usability analysis of two augmented reality headsets in visceral surgery.« Artificial Organs, 43 (7): 694-698.
https://doi.org/10.1111/aor.13396

Moosburner, S., Ritschl, P. V., Wiering, L., Gassner, J. M. G. V., Öllinger, R., Pratschke, J., Sauer, I. M., Raschzok, N. 2019. »Hohes Spenderalter bei Lebertransplantation.« Der Chirurg, 90 (9): 744-751.
https://doi.org/10.1007/s00104-019-0801-z

Moosburner, S., Sauer, I. M., Gassner, J. M. G. V., Schleicher, C., Bösebeck, D., Rahmel, A., Pratschke, J., Raschzok, N. 2019. »Macrosteatosis is a huge problem in liver transplantation—however, not the only one we face.« American Journal of Transplantation, 19 (9): 2661-2662.
https://doi.org/10.1111/ajt.15418

Siefert, J., Hillebrandt, K. H., Moosburner, S., Podrabsky, P., Geisel, D., Denecke, T., Unger, J. K., Sawitzki, B., Gül-Klein, S., Lippert, S., Tang, P., Reutzel-Selke, A., Morgul, M. H., Reske, A. W., Kafert-Kasting, S., Rüdinger, W., Oetvoes, J., Pratschke, J., Sauer, I. M., Raschzok, N. 2019. »Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model.« Cell Transplantation, 28 (1_suppl): 14S-24S.
https://doi.org/10.1177/0963689719885091

Truong, K., Schlickeiser, S., Vogt, K., Boës, D., Stanko, K., Appelt, C., Streitz, M., Grütz, G., Stobutzki, N., Meisel, C., Iwert, C., Tomiuk, S., Polansky, J. K., Pascher, A., Babel, N., Stervbo, U., Sauer, I., Gerlach, U., Sawitzki, B. 2019. »Killer-like receptors and GPR56 progressive expression defines cytokine production of human CD4+ memory T cells.« Nature Communications, 10 (1)
https://doi.org/10.1038/s41467-019-10018-1

Wabitsch, S., Benzing, C., Krenzien, F., Splith, K., Haber, P. K., Arnold, A., Nösser, M., Kamali, C., Hermann, F., Günther, C., Hirsch, D., Sauer, I. M., Pratschke, J., Schmelzle, M. 2019. »Human Stem Cells Promote Liver Regeneration After Partial Hepatectomy in BALB/C Nude Mice.« Journal of Surgical Research, 239: 191-200.
https://doi.org/10.1016/j.jss.2019.02.010

Brunnbauer, P., Leder, A., Kamali, C., Kamali, K., Keshi, E., Splith, K., Wabitsch, S., Haber, P., Atanasov, G., Feldbrügge, L., Sauer, I. M., Pratschke, J., Schmelzle, M., Krenzien, F. 2018. »The nanomolar sensing of nicotinamide adenine dinucleotide in human plasma using a cycling assay in albumin modified simulated body fluids.« Scientific Reports, 8 (1)
https://doi.org/10.1038/s41598-018-34350-6

Krenzien, F., Schmelzle, M., Struecker, B., Raschzok, N., Benzing, C., Jara, M., Bahra, M., Öllinger, R., Sauer, I. M., Pascher, A., Pratschke, J., Andreou, A. 2018. »Liver Transplantation and Liver Resection for Cirrhotic Patients with Hepatocellular Carcinoma: Comparison of Long-Term Survivals.« Journal of Gastrointestinal Surgery, 22 (5): 840-848.
https://doi.org/10.1007/s11605-018-3690-4

Major, R. D., Kluge, M., Jara, M., Nösser, M., Horner, R., Gassner, J., Struecker, B., Tang, P., Lippert, S., Reutzel-Selke, A., Geisel, D., Denecke, T., Stockmann, M., Pratschke, J., Sauer, I. M., Raschzok, N. 2018. »The Predictive Value of the Maximal Liver Function Capacity Test for the Isolation of Primary Human Hepatocytes.« Tissue Engineering Part C: Methods, 24 (3): 179-186.
https://doi.org/10.1089/ten.TEC.2017.0369

Moosburner, S., Gassner, J. M. G. V., Nösser, M., Pohl, J., Wyrwal, D., Claussen, F., Ritschl, P. V., Dragun, D., Pratschke, J., Sauer, I. M., Raschzok, N. 2018. »Prevalence of Steatosis Hepatis in theEurotransplantRegion: Impact on Graft Acceptance Rates.« HPB Surgery, 2018: 1-9.
https://doi.org/10.1155/2018/6094936

Müller, V., Mogl, M., Seika, P., Jöns, T., Sauer, I., Pratschke, J., Anuwong, A., Zorron, R. 2018. »How I Do It: New Dissector Device Allows for Effective Operative Field in Transoral Endoscopic Thyroid Surgery Using Vestibular Approach.« Surgical Innovation, 25 (5): 444-449.
https://doi.org/10.1177/1553350618785281

Neumann, C. C., von Hörschelmann, E., Reutzel-Selke, A., Seidel, E., Sauer, I. M., Pratschke, J., Bahra, M., Schmuck, R. B. 2018. »Tumor–stromal cross-talk modulating the therapeutic response in pancreatic cancer.« Hepatobiliary & Pancreatic Diseases International, 17 (5): 461-472.
https://doi.org/10.1016/j.hbpd.2018.09.004

Andreou A., Pesthy S., Struecker B., Dadras M., Raakow J., Knitter S., Duwe G., Sauer I. M., Beierle A. S., Denecke C., Chopra S., Pratschke J., Biebl M. 2017. »Incidence and Risk Factors of Symptomatic Hiatal Hernia Following Resection for Gastric and Esophageal Cancer.« Anticancer Research, 37 (12)
https://doi.org/10.21873/anticanres.12173

Belaschk, E., Rohn, S., Mukiibi, R., Reutzel-Selke, A., Tang, P., Sawitzki, B., Pratschke, J., Sauer, I. M., Mogl, M. T. 2017. »Isolation, Characterization and Cold Storage of Cells Isolated from Diseased Explanted Livers.« The International Journal of Artificial Organs, 40 (6): 294-306.
https://doi.org/10.5301/ijao.5000594

Butter, A., Aliyev, K., Hillebrandt, K., Raschzok, N., Kluge, M., Seiffert, N., Tang, P., Napierala, H., Muhamma, A. I., Reutzel‐Selke, A., Andreou, A., Pratschke, J., Sauer, I. M., Struecker, B. 2017. »Evolution of graft morphology and function after recellularization of decellularized rat livers.« Journal of Tissue Engineering and Regenerative Medicine, 12 (2)
https://doi.org/10.1002/term.2383

Duwe, G., Knitter, S., Pesthy, S., Beierle, A., Bahra, M., Schmelzle, M., Schmuck, R., Lohneis, P., Raschzok, N., Öllinger, R., Sinn, M., Struecker, B., Sauer, I., Pratschke, J., Andreou, A. 2017. »Hepatotoxicity following systemic therapy for colorectal liver metastases and the impact of chemotherapy-associated liver injury on outcomes after curative liver resection.« European Journal of Surgical Oncology, 43 (9): 1668-1681.
https://doi.org/10.1016/j.ejso.2017.05.008

Klein, F., Sauer, I. M., Pratschke, J., Bahra, M. 2017. »Bovine Serum Albumin-Glutaraldehyde Sealed Fish-Mouth Closure of the Pancreatic Remnant during Distal Pancreatectomy.« HPB Surgery, 2017: 1-7.
https://doi.org/10.1155/2017/9747421

Kluge, M., Leder, A., Hillebrandt, K. H., Struecker, B., Geisel, D., Denecke, T., Major, R. D., Reutzel-Selke, A., Tang, P., Lippert, S., Schmidt, C., Pratschke, J., Sauer, I. M., Raschzok, N. 2017. »The Magnetic Field of Magnetic Resonance Imaging Systems Does Not Affect Cells Labeled with Micrometer-Sized Iron Oxide Particles.« Tissue Engineering Part C: Methods, 23 (7): 412-421.
https://doi.org/10.1089/ten.TEC.2017.0118

Morgul, M. H., Splith, K., Leonhardt, C., Raschzok, N., Reutzel-Selke, A., Schmuck, R. B., Andreou, A., Atanasov, G., Benzing, C., Krenzien, F., Hau, H., Felgendreff, P., Klunk, S., Pratschke, J., Sauer, I. M., Schmelzle, M. 2017. »The value of microparticles in detecting acute rejection episodes after liver transplantation.« Biomarkers, 23 (1): 25-32.
https://doi.org/10.1080/1354750X.2017.1306754

Müller, V., Fikatas, P., Gül, S., Noesser, M., Fuehrer, K. t., Sauer, I., Pratschke, J., Zorron, R. 2017. »New technique for obersity surgery: Internal gastric plication technique using intragastric single-port (IGS-IGP) in experimental model.« ABCD. Arquivos Brasileiros de Cirurgia Digestiva (São Paulo), 30 (1): 60-64.
https://doi.org/10.1590/0102-6720201700010017

Napierala, H., Hillebrandt, K., Haep, N., Tang, P., Tintemann, M., Gassner, J., Noesser, M., Everwien, H., Seiffert, N., Kluge, M., Teegen, E., Polenz, D., Lippert, S., Geisel, D., Reutzel Selke, A., Raschzok, N., Andreou, A., Pratschke, J., Sauer, I. M., Struecker, B. 2017. »Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans.« Scientific Reports, 7 (1)
https://doi.org/10.1038/srep41777

Sauer, I. M., Queisner, M., Tang, P., Moosburner, S., Hoepfner, O., Horner, R., Lohmann, R., Pratschke, J. 2017. »Mixed Reality in Visceral Surgery.« Annals of Surgery, 266 (5): 706-712.
https://doi.org/doi:10.1097/SLA.0000000000002448

Struecker, B., Andreou, A., Chopra, S., Heilmann, A., Spenke, J., Denecke, C., Sauer, I., Bahra, M., Pratschke, J., Biebl, M. 2017. »Evaluation of Anastomotic Leak after Esophagectomy for Esophageal Cancer: Typical Time Point of Occurrence, Mode of Diagnosis, Value of Routine Radiocontrast Agent Studies and Therapeutic Options.« Digestive Surgery, 35 (5): 419-426.
https://doi.org/10.1159/000480357

Struecker, B., Chopra, S., Heilmann, A., Spenke, J., Denecke, C., Sauer, I. M., Bahra, M., Pratschke, J., Andreou, A., Biebl, M. 2017. »Routine Radiologic Contrast Agent Examination After Gastrectomy for Gastric Cancer Is Not Useful.« Journal of Gastrointestinal Surgery, 21 (5): 801-806.
https://doi.org/10.1007/s11605-017-3384-3

von Loeffelholz, C., Lieske, S., Neuschäfer-Rube, F., Willmes, D. M., Raschzok, N., Sauer, I. M., König, J., Fromm, M. F., Horn, P., Chatzigeorgiou, A., Pathe-Neuschäfer-Rube, A., Jordan, J., Pfeiffer, A. F., Mingrone, G., Bornstein, S. R., Stroehle, P., Harms, C., Wunderlich, F. T., Helfand, S. L., Bernier, M., de Cabo, R., Shulman, G. I., Chavakis, T., Püschel, G. P., Birkenfeld, A. L. 2017. »The human longevity gene homologINDYand interleukin-6 interact in hepatic lipid metabolism.« Hepatology, 66 (2): 616-630.
https://doi.org/10.1002/hep.29089

Andreou, A., Bahra, M., Schmelzle, M., Öllinger, R., Sucher, R., Sauer, I. M., Guel-Klein, S., Struecker, B., Eurich, D., Klein, F., Pascher, A., Pratschke, J., Seehofer, D. 2016. »Predictive factors for extrahepatic recurrence of hepatocellular carcinoma following liver transplantation.« Clinical Transplantation, 30 (7): 819-827.
https://doi.org/10.1111/ctr.12755

Andreou, A., Biebl, M., Dadras, M., Struecker, B., Sauer, I. M., Thuss-Patience, P. C., Chopra, S., Fikatas, P., Bahra, M., Seehofer, D., Pratschke, J., Schmidt, S. 2016. »Anastomotic leak predicts diminished long-term survival after resection for gastric and esophageal cancer.« Surgery, 160 (1): 191-203.
https://doi.org/10.1016/j.surg.2016.02.020

Andreou, A., Schmelzle, M., Sauer, I., Bahra, M., Pratschke, J. 2016. »Stellenwert des Proliferationsreizes auf die okkulte Mikrometastasierung sowie Rezidivhäufigkeit und Prognose nach Resektion von Lebermalignomen.« Zentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie, 141 (04): 375-382.
https://doi.org/10.1055/s-0042-108592

Horner, R., Kluge, M., Gassner, J., Nösser, M., Major, R. D., Reutzel-Selke, A., Leder, A. K., Struecker, B., Morgul, M. H., Pratschke, J., Sauer, I. M., Raschzok, N. 2016. »Hepatocyte Isolation After Laparoscopic Liver Resection.« Tissue Engineering Part C: Methods, 22 (9): 839-846.
https://doi.org/10.1089/ten.TEC.2016.0187

Kluge, M., Reutzel-Selke, A., Napierala, H., Hillebrandt, K. H., Major, R. D., Struecker, B., Leder, A., Siefert, J., Tang, P., Lippert, S., Sallmon, H., Seehofer, D., Pratschke, J., Sauer, I. M., Raschzok, N. 2016. »Human Hepatocyte Isolation: Does Portal Vein Embolization Affect the Outcome?« Tissue Engineering Part C: Methods, 22 (1): 38-48.
https://doi.org/10.1089/ten.TEC.2015.0190

Morgul, M. H., Klunk, S., Anastasiadou, Z., Gauger, U., Dietel, C., Reutzel-Selke, A., Felgendref, P., Hau, H., Tautenhahn, H., Schmuck, R. B., Raschzok, N., Sauer, I. M., Bartels, M. 2016. »Diagnosis of HCC for patients with cirrhosis using miRNA profiles of the tumor-surrounding tissue – A statistical model based on stepwise penalized logistic regression.« Experimental and Molecular Pathology, 101 (2): 165-171.
https://doi.org/10.1016/j.yexmp.2016.07.014

Raschzok, N., Reutzel-Selke, A., Schmuck, R. B., Tannus, L. M., Morgul, M. H., Dietel, C., Leder, A., Struecker, B., Lippert, S., Sallmon, H., Schmelzle, M., Bartels, M., Jonas, S., Pratschke, J., Sauer, I. M. 2016. »microRNA signatures in peripheral blood fail to detect acute cellular rejection after liver transplantation.« Biomarkers, 21 (8): 699-707.
https://doi.org/10.3109/1354750X.2016.1172113

Rohn, S., Schroeder, J., Riedel, H., Polenz, D., Stanko, K., Reutzel-Selke, A., Tang, P., Brusendorf, L., Raschzok, N., Neuhaus, P., Pratschke, J., Sawitzki, B., Sauer, I. M., Mogl, M. T. 2016. »Allogeneic Liver Transplantation and Subsequent Syngeneic Hepatocyte Transplantation in a Rat Model: Proof of Concept for in vivo Tissue Engineering.« Cells Tissues Organs, 201 (6): 399-411.
https://doi.org/10.1159/000445792

Schmuck, R. B., Nawrot, G., Fikatas, P., Reutzel-Selke, A., Pratschke, J., Sauer, I. M. 2016. »Single Pass Albumin Dialysis-A Dose-Finding Study to Define Optimal Albumin Concentration and Dialysate Flow.« Artificial Organs, 41 (2): 153-161.
https://doi.org/10.1111/aor.12736

Schmuck, R. B., Reutzel-Selke, A., Raschzok, N., Morgul, H. M., Struecker, B., Lippert, S., de Carvalho Fischer, C., Schmelzle, M., Boas-Knoop, S., Bahra, M., Pascher, A., Pratschke, J., Sauer, I. M. 2016. »Bile: miRNA pattern and protein-based biomarkers may predict acute cellular rejection after liver transplantation.« Biomarkers, 22 (1): 19-27.
https://doi.org/10.1080/1354750X.2016.1201538

Siefert, J., Hillebrandt, K. H., Kluge, M., Geisel, D., Podrabsky, P., Denecke, T., Nösser, M., Gassner, J., Reutzel-Selke, A., Strücker, B., Morgul, M. H., Guel-Klein, S., Unger, J. K., Reske, A., Pratschke, J., Sauer, I. M., Raschzok, N. 2016. »Computed tomography-based survey of the vascular anatomy of the juvenile Göttingen minipig.« Laboratory Animals, 51 (4): 388-396.
https://doi.org/10.1177/0023677216680238

Struecker, B., Andreou, A., Sauer, I. M., Pratschke, J., Seehofer, D. 2016. »Risk factors for bile leakage after hepatectomy.« Hepatobiliary & Pancreatic Diseases International, 15 (1): 12-13.
https://doi.org/10.1016/s1499-3872(15)60041-8

Struecker, B., Biebl, M., Dadras, M., Chopra, S., Denecke, C., Spenke, J., Heilmann, A., Bahra, M., Sauer, I. M., Pratschke, J., Andreou, A. 2016. »The Impact of Obesity on Outcomes Following Resection for Gastric Cancer.« Digestive Surgery, 34 (2): 133-141.
https://doi.org/10.1159/000449043

von Loeffelholz, C., Döcke, S., Lock, J. F., Lieske, S., Horn, P., Kriebel, J., Wahl, S., Singmann, P., de las Heras Gala, T., Grallert, H., Raschzok, N., Sauer, I. M., Heller, R., Jahreis, G., Claus, R. A., Bauer, M., Stockmann, M., Birkenfeld, A. L., Pfeiffer, A. F. 2016. »Increased lipogenesis in spite of upregulated hepatic 5'AMP-activated protein kinase in human non-alcoholic fatty liver.« Hepatology Research, 47 (9): 890-901.
https://doi.org/10.1111/hepr.12825

Andreou, A., Bahra, M., Guel, S., Struecker, B., Sauer, I. M., Klein, F., Pascher, A., Pratschke, J., Seehofer, D. 2015. »Tumor DNA Index and α-Fetoprotein Level Define Outcome following Liver Transplantation for Advanced Hepatocellular Carcinoma.« European Surgical Research, 55 (4): 302-318.
https://doi.org/10.1159/000439565

Hillebrandt, K., Polenz, D., Butter, A., Tang, P., Reutzel-Selke, A., Andreou, A., Napierala, H., Raschzok, N., Pratschke, J., Sauer, I. M., Struecker, B. 2015. »Procedure for Decellularization of Rat Livers in an Oscillating-pressure Perfusion Device.« Journal of Visualized Experiments, (102)
https://doi.org/10.3791/53029

Leder, A., Raschzok, N., Schmidt, C., Arabacioglu, D., Butter, A., Kolano, S., de Sousa Lisboa, L. S., Werner, W., Polenz, D., Reutzel-Selke, A., Pratschke, J., Sauer, I. M. 2015. »Micron-sized iron oxide-containing particles for microRNA-targeted manipulation and MRI-based tracking of transplanted cells.« Biomaterials, 51: 129-137.
https://doi.org/10.1016/j.biomaterials.2015.01.065

Raschzok, N., Reutzel-Selke, A., Schmuck, R. B., Morgul, M. H., Gauger, U., Prabowo, K. A., Tannus, L., Leder, A., Struecker, B., Boas-Knoop, S., Bartels, M., Jonas, S., Lojewski, C., Puhl, G., Seehofer, D., Bahra, M., Pascher, A., Pratschke, J., Sauer, I. M. 2015. »CD44 and CXCL9 serum protein levels predict the risk of clinically significant allograft rejection after liver transplantation.« Liver Transplantation, 21 (9): 1195-1207.
https://doi.org/10.1002/lt.24164

Raschzok, N., Sallmon, H., Pratschke, J., Sauer, I. M. 2015. »MicroRNAs in liver tissue engineering — New promises for failing organs.« Advanced Drug Delivery Reviews, 88: 67-77.
https://doi.org/10.1016/j.addr.2015.06.005

Sauer, I. M. 2015. »Tissue Engineered Grafts—160 Years After R. Virchow’s Omnis Cellula e Cellula.« Transplantation, 99 (3): 462-463.
https://doi.org/10.1097/TP.0000000000000646

Struecker, B., Hillebrandt, K., Raschzok, N., Jöhrens, K., Butter, A., Tang, P., Andreou, A., Napierala, H., Reutzel-Selke, A., Denecke, T., Pratschke, J., Sauer, I. M. 2015. »Implantation of a Tissue-Engineered Neo-Bile Duct in Domestic Pigs.« European Surgical Research, 56 (1-2): 61-75.
https://doi.org/10.1159/000441720

Struecker, B., Hillebrandt, K. H., Voitl, R., Butter, A., Schmuck, R. B., Reutzel-Selke, A., Geisel, D., Joehrens, K., Pickerodt, P. A., Raschzok, N., Puhl, G., Neuhaus, P., Pratschke, J., Sauer, I. M. 2015. »Porcine Liver Decellularization Under Oscillating Pressure Conditions: A Technical Refinement to Improve the Homogeneity of the Decellularization Process.« Tissue Engineering Part C: Methods, 21 (3): 303-313.
https://doi.org/10.1089/ten.TEC.2014.0321

Riedlinger, D., Bahra, M., Boas-Knoop, S., Lippert, S., Bradtmöller, M., Guse, K., Seehofer, D., Bova, R., Sauer, I. M., Neuhaus, P., Koch, A., Kamphues, C. 2014. »Hedgehog pathway as a potential treatment target in human cholangiocarcinoma.« Journal of Hepato-Biliary-Pancreatic Sciences, 21 (8): 607-615.
https://doi.org/10.1002/jhbp.107

Struecker, B., Butter, A., Hillebrandt, K., Polenz, D., Reutzel-Selke, A., Tang, P., Lippert, S., Leder, A., Rohn, S., Geisel, D., Denecke, T., Aliyev, K., Jöhrens, K., Raschzok, N., Neuhaus, P., Pratschke, J., Sauer, I. M. 2014. »Improved rat liver decellularization by arterial perfusion under oscillating pressure conditions.« Journal of Tissue Engineering and Regenerative Medicine, 11 (2): 531-541.
https://doi.org/10.1002/term.1948

Werner, W., Sallmon, H., Leder, A., Lippert, S., Reutzel-Selke, A., Morgül, M., Jonas, S., Dame, C., Neuhaus, P., Iacomini, J., Tullius, S. G., Sauer, I. M., Raschzok, N. 2014. »Independent effects of sham laparotomy and anesthesia on hepatic microRNA expression in rats.« BMC Research Notes, 7 (1): 702.
https://doi.org/10.1186/1756-0500-7-702

Döcke, S., Lock, J. F., Birkenfeld, A. L., Hoppe, S., Lieske, S., Rieger, A., Raschzok, N., Sauer, I. M., Florian, S., Osterhoff, M. A., Heller, R., Herrmann, K., Lindenmüller, S., Horn, P., Bauer, M., Weickert, M. O., Neuhaus, P., Stockmann, M., Möhlig, M., Pfeiffer, A. F. H., von Loeffelholz, C. 2013. »Elevated hepatic chemerin mRNA expression in human non-alcoholic fatty liver disease.« European Journal of Endocrinology, 169 (5): 547-557.
https://doi.org/10.1530/EJE-13-0112

Fikatas, P., Lee, J., Sauer, I., Schmidt, S., Seehofer, D., Puhl, G., Guckelberger, O. 2013. »APACHE III Score Is Superior to King's College Hospital Criteria, MELD score and APACHE II Score to Predict Outcomes After Liver Transplantation for Acute Liver Failure.« Transplantation Proceedings, 45 (6): 2295-2301.
https://doi.org/10.1016/j.transproceed.2013.02.125

Korup, S., Rietscher, J., Calvignac-Spencer, S., Trusch, F., Hofmann, J., Moens, U., Sauer, I., Voigt, S., Schmuck, R., Ehlers, B. 2013. »Identification of a Novel Human Polyomavirus in Organs of the Gastrointestinal Tract.« PLoS ONE, 8 (3): e58021.
https://doi.org/10.1371/journal.pone.0058021

Mogl, M. T., Albert, K., Pascher, A., Sauer, I., Puhl, G., Gül, S., Schönemann, C., Neuhaus, P., Guckelberger, O. 2013. »Survival Without Biliary Complications After Liver Transplant for Primary Sclerosing Cholangitis.« Experimental and Clinical Transplantation, 11 (6): 510-521.
https://doi.org/10.6002/ect.2013.0051

Raschzok, N., Langer, C. M., Schmidt, C., Lerche, K. H., Billecke, N., Nehls, K., Schlüter, N. B., Leder, A., Rohn, S., Mogl, M. T., Lüdemann, L., Stelter, L., Teichgräber, U. K., Neuhaus, P., Sauer, I. M. 2013. »Functionalizable Silica-Based Micron-Sized Iron Oxide Particles for Cellular Magnetic Resonance Imaging.« Cell Transplantation, 22 (11): 1959-1970.
https://doi.org/10.3727/096368912X661382

Stelter, L., Fuchs, S., Jungbluth, A. A., Ritter, G., Longo, V. A., Zanzonico, P., Raschzok, N., Sauer, I. M., Bomalaski, J. S., Larson, S. M. 2013. »Evaluation of Arginine Deiminase Treatment in Melanoma Xenografts Using 18F-FLT PET.« Molecular Imaging and Biology, 15 (6): 768-775.
https://doi.org/10.1007/s11307-013-0655-6

Struecker, B., Raschzok, N., Sauer, I. M. 2013. »Liver support strategies: cutting-edge technologies.« Nature Reviews Gastroenterology & Hepatology, 11 (3): 166-176.
https://doi.org/10.1038/nrgastro.2013.204

Tong, G., Endersfelder, S., Rosenthal, L., Wollersheim, S., Sauer, I. M., Bührer, C., Berger, F., Schmitt, K. R. L. 2013. »Effects of moderate and deep hypothermia on RNA-binding proteins RBM3 and CIRP expressions in murine hippocampal brain slices.« Brain Research, 1504: 74-84.
https://doi.org/10.1016/j.brainres.2013.01.041

Billecke, N., Raschzok, N., Rohn, S., Morgul, M. H., Schwartlander, R., Mogl, M., Wollersheim, S., Schmitt, K. R., Sauer, I. M. 2012. »An operational concept for long-term cinemicrography of cells in mono- and co-culture under highly controlled conditions – The SlideObserver.« Journal of Biotechnology, 159 (1-2): 83-89.
https://doi.org/10.1016/j.jbiotec.2012.01.033

Kehr, D., Raschzok, N., Sauer, I. 2012. »A Novel Cannulation Technique for Isolation of Human Hepatocytes from Explanted Diseased Whole Livers.« Transplantation Proceedings, 44 (4): 999-1001.
https://doi.org/10.1016/j.transproceed.2012.03.006

Pless, G., Sauer, I. M., Rauen, U. 2012. »Improvement of the Cold Storage of Isolated Human Hepatocytes.« Cell Transplantation, 21 (1): 23-37.
https://doi.org/10.3727/096368911X580509

Raschzok, N., Pinkernelle, J., Billecke, N., Nehls, K., Powerski, M., Sauer, I. M., Teichgräber, U. 2012. »Feasibility of Fast Dynamic MRI for Noninvasive Monitoring During Ectopic Liver Cell Transplantation to the Spleen in a Porcine Model.« American Journal of Roentgenology, 198 (6): 1417-1423.
https://doi.org/10.2214/AJR.11.7742

Raschzok, N., Sallmon, H., Dame, C., Sauer, I. M. 2012. »Liver regeneration after partial hepatectomy: inconsistent results of expression screenings for human, mouse, and rat microRNAs.« American Journal of Physiology-Gastrointestinal and Liver Physiology, 302 (4): G470-G471.
https://doi.org/10.1152/ajpgi.00494.2011

Kammer, N. N., Billecke, N., Morgul, M. H., Adonopoulou, M. K., Mogl, M., Huang, M. D., Florek, S., Schmitt, K. R., Raschzok, N., Sauer, I. M. 2011. »Labeling of Primary Human Hepatocytes With Micron-Sized Iron Oxide Particles in Suspension Culture Suitable for Large-Scale Preparation.« Artificial Organs, 35 (4): E91-E100.
https://doi.org/10.1111/j.1525-1594.2010.01177.x

Rago, G., Langer, C. M., Brackman, C., Day, J. P., Domke, K. F., Raschzok, N., Schmidt, C., Sauer, I. M., Enejder, A., Mogl, M. T., Bonn, M. 2011. »CARS microscopy for the visualization of micrometer-sized iron oxide MRI contrast agents in living cells.« Biomedical Optics Express, 2 (9): 2470.
https://doi.org/10.1364/BOE.2.002470

Raschzok, N., Werner, W., Sallmon, H., Billecke, N., Dame, C., Neuhaus, P., Sauer, I. M. 2011. »Temporal expression profiles indicate a primary function for microRNA during the peak of DNA replication after rat partial hepatectomy.« American Journal of Physiology-Regulatory, Integrative and Comparative Physiology, 300 (6): R1363-R1372.
https://doi.org/10.1152/ajpregu.00632.2010

Ringe, H., Varnholt, V., Zimmering, M., Luck, W., Gratopp, A., König, K., Reich, S., Sauer, I. M., Gaedicke, G., Querfeld, U. 2011. »Continuous veno-venous single-pass albumin hemodiafiltration in children with acute liver failure*.« Pediatric Critical Care Medicine, 12 (3): 257-264.
https://doi.org/10.1097/PCC.0b013e3181f35fa2

Diestel, A., Troeller, S., Billecke, N., Sauer, I. M., Berger, F., Schmitt, K. R. L. 2010. »Mechanisms of hypothermia-induced cell protection mediated by microglial cellsin vitro.« European Journal of Neuroscience, 31 (5): 779-787.
https://doi.org/10.1111/j.1460-9568.2010.07128.x

Raschzok, N., Muecke, D. A., Adonopoulou, M. K., Billecke, N., Werner, W., Kammer, N. N., Zielinski, A., Behringer, P. A., Ringel, F., Huang, M. D., Neuhaus, P., Teichgräber, U., Sauer, I. M. 2010. »In Vitro Evaluation of Magnetic Resonance Imaging Contrast Agents for Labeling Human Liver Cells: Implications for Clinical Translation.« Molecular Imaging and Biology, 13 (4): 613-622.
https://doi.org/10.1007/s11307-010-0405-y

Raschzok, N., Teichgräber, U., Billecke, N., Zielinski, A., Steinz, K., Kammer, N. N., Morgul, M. H., Schmeisser, S., Adonopoulou, M. K., Morawietz, L., Hiebl, B., Schwartlander, R., Rüdinger, W., Hamm, B., Neuhaus, P., Sauer, I. M. 2010. »Monitoring of Liver Cell Transplantation in a Preclinical Swine Model Using Magnetic Resonance Imaging.« Cell Medicine, 1 (3): 123-136.
https://doi.org/10.3727/215517910X551053

Schmeding, M., Sauer, I., Hartwig, K., Theruvath, T., Pratschke, J., Neuhaus, R., Neuhaus, P., Neumann, U. P. 2010. »Aging of the liver graft and functional quality in the absence of recurrent disease: A 10 year histological follow-up.« Annals of Transplantation, 15 (1): 5-13.
https://doi.org/10.12659/aot.880562

Deurholt, T., van Til, N. P., Chhatta, A. A., ten Bloemendaal, L., Schwartlander, R., Payne, C., Plevris, J. N., Sauer, I. M., Chamuleau, R. A., Elferink, R., Seppen, J., Hoekstra, R. 2009. »Novel immortalized human fetal liver cell line, cBAL111, has the potential to differentiate into functional hepatocytes.« BMC Biotechnology, 9 (1): 89.
https://doi.org/10.1186/1472-6750-9-89

Diestel, A., Billecke, N., Roessler, J., Schmitt, B., Troeller, S., Schwartlander, R., Berger, F., Sauer, I. M., Schmitt, K. R. L. 2009. »Methylprednisolone and Tacrolimus Prevent Hypothermia-Induced Endothelial Dysfunction.« The Journal of Heart and Lung Transplantation, 28 (7): 718-724.
https://doi.org/10.1016/j.healun.2009.04.003

Kohler, S., Gerlach, U., Guckelberger, O., Sauer, I. M., Jörres, D., Neuhaus, P., Pratschke, J., Pascher, A. 2009. »Successful treatment of invasive sphenoidal, pulmonary and intracerebral aspergillosis after multivisceral transplantation.« Transplant International, 22 (5): 589-591.
https://doi.org/10.1111/j.1432-2277.2008.00817.x

Raschzok, N., Billecke, N., Kammer, N. N., Morgul, M. H., Adonopoulou, M. K., Sauer, I. M., Florek, S., Becker-Roß, H., Huang, M. D. 2009. »Quantification of Cell Labeling with Micron-Sized Iron Oxide Particles Using Continuum Source Atomic Absorption Spectrometry.« Tissue Engineering Part C: Methods, 15 (4): 681-686.
https://doi.org/10.1089/ten.tec.2008.0675

Stelter, L., Pinkernelle, J. G., Michel, R., Schwartländer, R., Raschzok, N., Morgul, M. H., Koch, M., Denecke, T., Ruf, J., Bäumler, H., Jordan, A., Hamm, B., Sauer, I. M., Teichgräber, U. 2009. »Modification of Aminosilanized Superparamagnetic Nanoparticles: Feasibility of Multimodal Detection Using 3T MRI, Small Animal PET, and Fluorescence Imaging.« Molecular Imaging and Biology, 12 (1): 25-34.
https://doi.org/10.1007/s11307-009-0237-9

Kohler, S., Pascher, A., Junge, G., Sauer, I. M., Nagy, M., Schönemann, C., Koch, M., Neumann, U., Pratschke, J., Neuhaus, P. 2008. »Graft versus host disease after liver transplantation – a single center experience and review of literature.« Transplant International, 21 (5): 441-451.
https://doi.org/10.1111/j.1432-2277.2007.00625.x

Morgul, M. H., Raschzok, N., Schwartlander, R., Vondran, F., Michel, R., Stelter, L., Pinkernelle, J., Jordan, A., Teichgraber, U., Sauer, I. M. 2008. »Tracking of Primary Human Hepatocytes with Clinical MRI: Initial Results with Tat-Peptide Modified Superparamagnetic Iron Oxide Particles.« The International Journal of Artificial Organs, 31 (3): 252-257.
https://doi.org/10.1177/039139880803100309

Raschzok, N., Morgul, M. H., Pinkernelle, J., Vondran, F. W. R., Billecke, N., Kammer, N. N., Pless, G., Adonopoulou, M. K., Leist, C., Stelter, L., Teichgraber, U., Schwartlander, R., Sauer, I. M. 2008. »Imaging of primary human hepatocytes performed with micron-sized iron oxide particles and clinical magnetic resonance tomography.« Journal of Cellular and Molecular Medicine, 12 (4): 1384-1394.
https://doi.org/10.1111/j.1582-4934.2008.00343.x

Spinelli, A., Schumacher, G., Benckert, C., Sauer, I., Schmeding, M., Glanemann, M., Neumann, U., Jonas, S., Neuhaus, P. 2008. »Surgical treatment of a leiomyosarcoma of the inferior vena cava involving the hepatic and renal veins confluences: Technical aspects.« European Journal of Surgical Oncology (EJSO), 34 (7): 831-835.
https://doi.org/10.1016/j.ejso.2007.01.015

Vondran, F. W. R., Katenz, E., Schwartlander, R., Morgul, M. H., Raschzok, N., Gong, X., Cheng, X., Kehr, D., Sauer, I. M. 2008. »Isolation of Primary Human Hepatocytes After Partial Hepatectomy: Criteria for Identification of the Most Promising Liver Specimen.« Artificial Organs, 32 (3): 205-213.
https://doi.org/10.1111/j.1525-1594.2007.00524.x

Poyck, P., Pless, G., Hoekstra, R., Roth, S., Van Wijk, A., Schwartländer, R., Van Gulik, T., Sauer, I., Chamuleau, R. 2007. »In Vitro Comparison of Two Bioartificial Liver Support Systems: MELS CellModule and AMC-BAL.« The International Journal of Artificial Organs, 30 (3): 183-191.
https://doi.org/10.1177/039139880703000302

Schwartlander, R., Schmid, J., Brandenburg, B., Katenz, E., Vondran, F. W. R., Pless, G., Cheng, X., Pascher, A., Neuhaus, P., Sauer, I. M. 2007. »Continuously Microscopically Observed and Process-Controlled Cell Culture Within the SlideReactor: Proof of a New Concept for Cell Characterization.« Tissue Engineering, 13 (1): 187-196.
https://doi.org/10.1089/ten.2006.0071

Singh, V., Grötzinger, C., Nowak, K. W., Zacharias, S., Göncz, E., Pless, G., Sauer, I. M., Eichhorn, I., Pfeiffer-Guglielmi, B., Hamprecht, B., Wiedenmann, B., Plöckinger, U., Strowski, M. Z. 2007. »Somatostatin Receptor Subtype-2-Deficient Mice with Diet-Induced Obesity Have Hyperglycemia, Nonfasting Hyperglucagonemia, and Decreased Hepatic Glycogen Deposition.« Endocrinology, 148 (8): 3887-3899.
https://doi.org/10.1210/en.2006-1659

Katenz, E., Vondran, F. W. R., Schwartlander, R., Pless, G., Gong, X., Cheng, X., Neuhaus, P., Sauer, I. M. 2006. »Cryopreservation of primary human hepatocytes: The benefit of trehalose as an additional cryoprotective agent.« Liver Transplantation, 13 (1): 38-45.
https://doi.org/10.1002/lt.20921

Pless, G., Steffen, I., Zeilinger, K., Sauer, I. M., Katenz, E., Kehr, D. C., Roth, S., Mieder, T., Schwartlander, R., Müller, C., Wegner, B., Hout, M. S., Gerlach, J. C. 2006. »Evaluation of Primary Human Liver Cells in Bioreactor Cultures for Extracorporeal Liver Support on the Basis of Urea Production.« Artificial Organs, 30 (9): 686-694.
https://doi.org/10.1111/j.1525-1594.2006.00285.x

Sauer, I. M., Baurmeister, U. 2006. »Cell-Free Artificial Liver Support.« Therapeutic Apheresis and Dialysis, 10 (2): 105-107.
https://doi.org/10.1111/j.1744-9987.2006.00350.x

Sauer, I. M., Obermeyer, N., Kardassis, D., Theruvath, T., Gerlach, J. C. 2006. »Development of a Hybrid Liver Support System.« Annals of the New York Academy of Sciences, 944 (1): 308-319.
https://doi.org/10.1111/j.1749-6632.2001.tb03843.x

Spinelli, A., Sauer, I. M. ????? 2006. »Extended surgical resection for xanthogranulomatous cholecystitis mimicking advanced gallbladder carcinoma: A case report and review of literature.« World Journal of Gastroenterology, 12 (14): 2293.
https://doi.org/10.3748/wjg.v12.i14.2293

Brandenburg, B., Stockl, L., Gutzeit, C., Roos, M., Lupberger, J., Schwartlander, R., Gelderblom, H., Sauer, I. M., Hofschneider, P. H., Hildt, E. 2005. »A novel system for efficient gene transfer into primary human hepatocytes via cell-permeable hepatitis B virus-like particle.« Hepatology, 42 (6): 1300-1309.
https://doi.org/10.1002/hep.20950

Pascher, A., Klupp, J., Schulz, R. J., Kohler, S., Junge, G., Sauer, I. M., Veltzke-Schlieker, W., Adler, A., Guckelberger, O., Nüssler, N. C., Dignass, A., Langrehr, J. M., Neuhaus, P. 2005. »Klinische Ergebnisse der Dünndarm- und Multiviszeraltransplantation an der Berliner Charité.« DMW - Deutsche Medizinische Wochenschrift, 130 (8): 387-392.
https://doi.org/10.1055/s-2005-863062

Pless, G., Sauer, I. 2005. »Bioartificial Liver: Current Status.« Transplantation Proceedings, 37 (9): 3893-3895.
https://doi.org/10.1016/j.transproceed.2005.09.113

Sauer, I. M., Bialek, D., Efimova, E., Schwartlander, R., Pless, G., Neuhaus, P. 2005. »"Blogs" and "Wikis" Are Valuable Software Tools for Communication Within Research Groups.« Artificial Organs, 29 (1): 82-83.
https://doi.org/10.1111/j.1525-1594.2004.29005.x

Sauer, I. M., Schwartlander, R., Schmid, J., Efimova, E., Vondran, F. W., Kehr, D., Pless, G., Spinelli, A., Brandenburg, B., Hildt, E., Neuhaus, P. 2005. »The SlideReactor-A Simple Hollow Fiber Based Bioreactor Suitable for Light Microscopy.« Artificial Organs, 29 (3): 264-267.
https://doi.org/10.1111/j.1525-1594.2005.29049.x

Sauer, I. M., Schwartlander, R., Van der Jagt, O., Steffen, I., Efimova, E., Pless, G., Kehr, D. C., Kardassis, D., Fruhauf, J. H., Gerlach, J. C., Neuhaus, P. 2005. »In Vitro Evaluation of the Transportability of Viable Primary Human Liver Cells Originating From Discarded Donor Organs in Bioreactors.« Artificial Organs, 29 (2): 144-151.
https://doi.org/10.1111/j.1525-1594.2005.29025.x

Vanholder, R., del Canizo, J. F., Sauer, I. M., Stegmayr, B. 2005. »The European Artificial Organ Scene: Present Status.« Artificial Organs, 29 (6): 498-506.
https://doi.org/10.1111/j.1525-1594.2005.29079.x

Sauer, I. M., Goetz, M., Steffen, I., Walter, G., Kehr, D. C., Schwartlander, R., Hwang, Y. J., Pascher, A., Gerlach, J. C., Neuhaus, P. 2004. »In vitro comparison of the molecular adsorbent recirculation system (MARS) and single-pass albumin dialysis (SPAD).« Hepatology, 39 (5): 1408-1414.
https://doi.org/10.1002/hep.20195

Senf, R., Klingel, R., Kurz, S., Tullius, S., Sauer, I., Frei, U., Schindler, R. 2004. »Bilirubin-Adsorption in 23 Critically Ill Patients with Liver Failure.« The International Journal of Artificial Organs, 27 (8): 717-722.
https://doi.org/10.1177/039139880402700810

Zeilinger, K., Holland, G., Sauer, I. M., Efimova, E., Kardassis, D., Obermayer, N., Liu, M., Neuhaus, P., Gerlach, J. C. 2004. »Time Course of Primary Liver Cell Reorganization in Three-Dimensional High-Density Bioreactors for Extracorporeal Liver Support: An Immunohistochemical and Ultrastructural Study.« Tissue Engineering, 10 (7-8): 1113-1124.
https://doi.org/10.1089/ten.2004.10.1113

Gerlach, J. C., Mutig, K., Sauer, I. M., Schrade, P., Efimova, E., Mieder, T., Naumann, G., Grunwald, A., Pless, G., Mas, A., Bachmann, S., Neuhaus, P., Zeilinger, K. 2003. »Use of primary human liver cells originating from discarded grafts in a bioreactor for liver support therapy and the prospects of culturing adult liver stem cells in bioreactors: a morphologic study.« Transplantation, 76 (5): 781-786.
https://doi.org/10.1097/01.TP.0000083319.36931.32

Gerlach, J. C., Zeilinger, K., Grebe, A., Puhl, G., Pless, G., Sauer, I., Grünwald, A., Schnoy, N., Müller, C., Neuhaus, P. 2003. »Recovery of Preservation-Injured Primary Human Hepatocytes and Nonparenchymal Cells to Tissuelike Structures in Large-Scale Bioreactors for Liver Support: An Initial Transmission Electron Microscopy Study.« Journal of Investigative Surgery, 16 (2): 83-92.
https://doi.org/10.1080/08941930390194370

Irgang, M., Sauer, I. M., Karlas, A., Zeilinger, K., Gerlach, J. C., Kurth, R., Neuhaus, P., Denner, J. 2003. »Porcine endogenous retroviruses: no infection in patients treated with a bioreactor based on porcine liver cells.« Journal of Clinical Virology, 28 (2): 141-154.
https://doi.org/10.1016/s1386-6532(02)00275-5

Pascher, A., Radke, C., Dignass, A., Schulz, R., Sauer, I. M., Platz, K., Klupp, J., Neuhaus, P., Müller, A. R. 2003. »Late Graft Loss After Intestinal Transplantation in an Adult Patient as a Result of Necrotizing Enterocolitis.« American Journal of Transplantation, 3 (8): 1033-1035.
https://doi.org/10.1034/j.1600-6143.2003.00163.x

Pascher, A., Radke, C., Dignass, A., Schulz, R. J., Veltzke-Schlieker, W., Adler, A., Sauer, I. M., Platz, K., Klupp, J., Volk, H., Neuhaus, P., Mueller, A. R. 2003. »Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation.« Transplantation, 76 (3): 615-618.
https://doi.org/10.1097/01.TP.0000072804.41125.82

Sauer, I. M., Kardassis, D., Zeillinger, K., Pascher, A., Gruenwald, A., Pless, G., Irgang, M., Kraemer, M., Puhl, G., Frank, J., Müller, A. R., Steinmüller, T., Denner, J., Neuhaus, P., Gerlach, J. C. 2003. »Clinical extracorporeal hybrid liver support - phase I study with primary porcine liver cells.« Xenotransplantation, 10 (5): 460-469.
https://doi.org/10.1034/j.1399-3089.2003.00062.x

Sauer, I. M., Zeilinger, K., Pless, G., Kardassis, D., Theruvath, T., Pascher, A., Goetz, M., Neuhaus, P., Gerlach, J. C. 2003. »Extracorporeal liver support based on primary human liver cells and albumin dialysis – treatment of a patient with primary graft non-function.« Journal of Hepatology, 39 (4): 649-653.
https://doi.org/10.1016/s0168-8278(03)00348-9

Gerlach, J., Zeilinger, K., Sauer, I., Mieder, T., Naumann, G., Grünwald, A., Pless, G., Holland, G., Mas, A., Vienken, J., Neuhaus, P. 2002. »Extracorporeal Liver Support: Porcine or Human Cell Based Systems?« The International Journal of Artificial Organs, 25 (10): 1013-1018.
https://doi.org/10.1177/039139880202501017

Mueller, A., Pascher, A., Platz, K., Nüssler, N., Schulz, R., Horch, D., Melitz, T., Sauer, I., Eisele, R., Settmacher, U., Dignass, A., Lopez-Henninen, E., Weidemann, H., Neuhaus, P. 2002. »Modified surgical technique in clinical small bowel transplantation: donor and recipient management.« Transplantation Proceedings, 34 (6): 2265-2267.
https://doi.org/10.1016/s0041-1345(02)03229-3

Mundt, A., Puhl, G., Müller, A., Sauer, I., Müller, C., Richard, R., Fotopoulou, C., Doll, R., Gäbelein, G., Höhn, W., Hofbauer, R., Neuhaus, P., Gerlach, J. 2002. »A Method to assess Biochemical Activity of Liver Cells during Clinical Application of Extracorporeal Hybrid Liver Support.« The International Journal of Artificial Organs, 25 (6): 542-548.
https://doi.org/10.1177/039139880202500609

Pascher, A., Sauer, I., Neuhaus, P. 2002. »Analysis of Allogeneic versus Xenogeneic Auxiliary Organ Perfusion in Liver Failure Reveals Superior Efficacy of Human Livers.« The International Journal of Artificial Organs, 25 (10): 1006-1012.
https://doi.org/10.1177/039139880202501016

Pascher, A., Sauer, I., Schulz, R., Platz, K., Theruvath, T., Dignass, A., Radke, C., Neuhaus, P., Mueller, A. 2002. »Monitoring of immunosuppression after clinical small bowel transplantation.« Transplantation Proceedings, 34 (3): 931-933.
https://doi.org/10.1016/s0041-1345(02)02676-3

Pascher, A., Sauer, I. M., Hammer, C., Gerlach, J. C., Neuhaus, P. 2002. »Extracorporeal liver perfusion as hepatic assist in acute liver failure: a review of world experience.« Xenotransplantation, 9 (5): 309-324.
https://doi.org/10.1034/j.1399-3089.2002.01076.x

Pascher, A., Sauer, I.M. 2002. »Donor evaluation, donor risks, donor outcome, and donor quality of life in adult-to-adult living donor liver transplantation.« Liver Transplantation, 8 (9): 829-837.
https://doi.org/10.1053/jlts.2002.34896

Platz, K., Pascher, A., Schulz, R., Nüssler, N., Sauer, I., Settmacher, U., Eisele, R., Dignass, A., Lopez-Henninen, E., Neuhaus, P., Mueller, A. 2002. »Use of inferior mesenteric vein for venous anastomosis in clinical small bowel transplantation.« Transplantation Proceedings, 34 (3): 906-907.
https://doi.org/10.1016/s0041-1345(02)02662-3

Sauer, I., Zeilinger, K., Obermayer, N., Pless, G., Grünwald, A., Pascher, A., Mieder, T., Roth, S., Goetz, M., Kardassis, D., Mas, A., Neuhaus, P., Gerlach, J. 2002. »Primary Human Liver Cells as Source for Modular Extracorporeal Liver Support - a Preliminary Report.« The International Journal of Artificial Organs, 25 (10): 1001-1005.
https://doi.org/10.1177/039139880202501015

Sauer, I. M., Gerlach, J. C. 2002. »Modular Extracorporeal Liver Support.« Artificial Organs, 26 (8): 703-706.
https://doi.org/10.1046/j.1525-1594.2002.06931_1.x

Sauer, I. M., Neuhaus, P., Gerlach, J. C. 2002. »Concept for Modular Extracorporeal Liver Support for the Treatment of Acute Hepatic Failure.« Metabolic Brain Disease, 17 (4): 477-484.
https://doi.org/10.1023/a:1021938708670

Steinmüller, T., Pascher, A., Sauer, I., Theruvath, T., Müller, A., Settmacher, U., Neuhaus, P. 2002. »Living-donation liver transplantation for hepatocellular carcinoma: time to drop the limitations?« Transplantation Proceedings, 34 (6): 2263-2264.
https://doi.org/10.1016/s0041-1345(02)03228-1

Steinmüller, T., Pascher, A., Sauer, I. M., Theruvath, T., Müller, A. R., Settmacher, U., Neuhaus, P. 2002. »Lebendspende-Lebertransplantation des rechten Leberlappens zwischen Erwachsenen.« DMW - Deutsche Medizinische Wochenschrift, 127 (20): 1067-1071.
https://doi.org/10.1055/s-2002-30123

Zeilinger, K., Sauer, I. M., Pless, G., Strobel, C., Rudzitis, J., Wang, A., Nüssler, A. K., Grebe, A., Mao, L., Auth, S. H., Unger, J., Neuhaus, P., Gerlach, J. C. 2002. »Three-dimensional Co-culture of Primary Human Liver Cells in Bioreactors for In Vitro Drug Studies: Effects of the Initial Cell Quality on the Long-term Maintenance of Hepatocyte-specific Functions.« Alternatives to Laboratory Animals, 30 (5): 525-538.
https://doi.org/10.1177/026119290203000506

Sauer, I., Pascher, A., Steinmüller, T., Settmacher, U., Müller, A., Bechstein, W., Neuhaus, P. 2001. »Split liver and living donation liver transplantation: the Berlin experience.« Transplantation Proceedings, 33 (1-2): 1459-1460.
https://doi.org/10.1016/s0041-1345(00)02551-3

Sauer, I. M., Frank, J., Spiegelberg, A., Bücherl, E. S. 2000. »Ovalis TAH: Development and In Vitro Testing of a New Electromechanical Energy Converter for a Total Artificial Heart.« ASAIO Journal, 46 (6): 744-748.
https://doi.org/10.1097/00002480-200011000-00017