PD Dr. med. Thomas Picht
Thomas Picht is a Neurosurgeon, head of the Image Guidance Lab and co-director of the Berlin Simulation and Training Center of the Charité - Universitätsmedizin Berlin.
His research group deals with non-invasive brain function diagnostics, connectivity analyses and neuromodulation with the aim of optimally treating brain tumors with individualized therapy concepts.
Further focal points are the research of modern visualization strategies for the understanding and mediation of spatially complex structures as well as the establishment of novel simulation concepts in education and surgical practice. His research group is in close contact with a large number of medical device manufacturers and start-ups.
His comprehensive clinical and scientific experience in dealing with the highly dynamic materiality of the brain is decisive for the Cutting project.
Charité – Universitätsmedizin Berlin
Charitéplatz 1
10117 Berlin
Brain Surgery, Brain Mapping, Network Neuroscience
Articles
Tuncer, M., Salvati, L., Grittner, U., Hardt, J., Schilling, R., Bährend, I., Silva, L., Fekonja, L., Faust, K., Vajkoczy, P., Rosenstock, T., Picht, T. 2021. »Towards a tractography-based risk stratification model for language area associated gliomas.« NeuroImage: Clinical, 29, 102541. https://doi.org/10.1016/j.nicl.2020.102541
Wang, Z., Dreyer, F., Pulvermüller, F., Ntemou, E., Vajkoczy, P., Fekonja, L., Picht, T. 2021. »Support vector machine based aphasia classification of transcranial magnetic stimulation language mapping in brain tumor patients.« NeuroImage: Clinical, 29, 102536. https://doi.org/10.1016/j.nicl.2020.102536
Fekonja, L., Wang, Z., Bährend, I., Rosenstock, T., Rösler, J., Wallmeroth, L., Vajkoczy, P., Picht, T. 2019. »Manual for clinical language tractography.« Acta Neurochirurgica, 161, (6): 1125-1137. https://doi.org/10.1007/s00701-019-03899-0
Schwarzer, V., Bährend, I., Rosenstock, T., Dreyer, F., Vajkoczy, P., Picht, T. 2018. »Aphasia and cognitive impairment decrease the reliability of rnTMS language mapping.« Acta Neurochirurgica, 160, (2): 343. https://doi.org/10.1007/s00701-017-3397-4
Raffa, G., Bährend, I., Schneider, H., Faust, K., Germanò, A., Vajkoczy, P., Picht, T. 2016. »A novel technique for region and linguistic specific nTMS-based DTI fiber tracking of language pathways in brain tumor patients.« Frontiers in Neuroscience, 10, (Dec): https://doi.org/10.3389/fnins.2016.00552
Picht, T., Krieg, S., Sollmann, N., Rösler, J., Niraula, B., Neuvonen, T., Savolainen, P., Lioumis, P., Mäkelä, J., Deletis, V., Meyer, B., Vajkoczy, P., Ringel, F. 2013. »A comparison of language mapping by preoperative navigated transcranial magnetic stimulation and direct cortical stimulation during awake surgery.« Neurosurgery, 72, (5): 808. https://doi.org/10.1227/NEU.0b013e3182889e01
Frey, D., Strack, V., Wiener, E., Jussen, D., Vajkoczy, P., Picht, T. 2012. »A new approach for corticospinal tract reconstruction based on navigated transcranial stimulation and standardized fractional anisotropy values.« NeuroImage, 62, (3): 1600. https://doi.org/10.1016/j.neuroimage.2012.05.059
Lioumis, P., Zhdanov, A., Mäkelä, N., Lehtinen, H., Wilenius, J., Neuvonen, T., Hannula, H., Deletis, V., Picht, T., Mäkelä, J. 2012. »A novel approach for documenting naming errors induced by navigated transcranial magnetic stimulation.« Journal of Neuroscience Methods, 204, (2): 349. https://doi.org/10.1016/j.jneumeth.2011.11.003
Picht, T., Schulz, J., Hanna, M., Schmidt, S., Suess, O., Vajkoczy, P. 2012. »Assessment of the influence of navigated transcranial magnetic stimulation on surgical planning for tumors in or near the motor cortex.« Neurosurgery, 70, (5): 1248. https://doi.org/10.1227/NEU.0b013e318243881e
Picht, T., Strack, V., Schulz, J., Zdunczyk, A., Frey, D., Schmidt, S., Vajkoczy, P. 2012. »Assessing the functional status of the motor system in brain tumor patients using transcranial magnetic stimulation.« Acta Neurochirurgica, 154, (11): 2075. https://doi.org/10.1007/s00701-012-1494-y
Conference Proceedings
Fekonja, L. S., Wang, Z., Vajkoczy, P., Picht, T. 2019. »Along-tract statistical analysis to detect early corticospinal tract impairment in brain tumour patients. Along-tract statistische Analyse zurFrüherkennung von Beeinträchtigungen dercorticospinalen Faserbahnbei Gerhirntumorpatienten.« Meeting Abstract. Deutsche Gesellschaft für Neurochirurgie. 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie. 12.05. - 15.05.2019, Würzburg. https://doi.org/10.3205/19DGNC496
Fekonja, L. S., Wang, Z., Vajkoczy, P., Picht, T. 2019. »Automated tract segmentation in language tumour patients. Automatisierte Faserbahnsegmentierung bei Sprachtumorpatienten.« Meeting Abstract. 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC) Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie, 12.05. - 15.05.2019, Würzburg. https://doi.org/10.3205/19DGNC303
Wang, Z., Fekonja, L., Vajkoczy, P., Picht, T. 2019. »rnTMS language speech mapping analysis in MNI space reveals neuronal functional reorganisation rnTMS Sprachmapping-Analyse im MNI space zeigt neuronale funktionale Reorganisation.« Deutsche Gesellschaft für Neurochirurgie. 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie. Würzburg, 12.-15.05.2019. DocP161. Düsseldorf: German Medical Science GMS Publishing House; 2019, https://doi.org/10.3205/19DGNC498
Fekonja, L. S., Bährend, I., Schneider, H., Vajkoczy, P., Picht, T. 2018. »The Impact of different tractography algorithms on fiber tract visualization.« Meeting Abstract. 69. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Mexikanischen und Kolumbianischen Gesellschaft für Neurochirurgie. Münster, 03.-06.06.2018. DocV072. Düsseldorf: German Medical Science GMS Publishing House, https://doi.org/10.3205/18DGNC073
Software Publications
Fekonja, L. S., Wang, Z., Aydogan, D. B., Roine, T., Engelhardt, M., Dreyer, F. R., Vajkoczy, P., Picht, T. 2020. Code used in article "CSD-based metric for along-tract statistical analysis in primary motor tumor patients". https://doi.org/10.5281/zenodo.3732348
Mewes, D., Tournier, J-D., Picht, T., Fekonja, L. S. 2020. Implementation of OpenIGTLink tool in MRtrix3's mrview. mrtrix3-v0.1. https://doi.org/10.5281/ZENODO.3755569
Wang, Z., Fekonja, L. S., Dreyer, F., Vajkoczy, P., Picht, T. 2020. SVM code for article: Analysis of transcranial magnetic stimulation for object naming with machine learning classification shows reorganisation patterns in tumor patients. http://doi.org/10.5281/zenodo.3727664
Talks & Presentations
Fekonja, L. S., Wang, Z., Vajkoczy, P., Picht, T. Automated tract segmentation in language tumour patients. Automatisierte Faserbahnsegmentierung bei Sprachtumorpatienten. Poster presentation at 70. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit der Skandinavischen Gesellschaft für Neurochirurgie. Würzburg, 12.-15.05.2019. 14 May 2019.
External Grants, Fellowships, Scholarships & Residencies
Fekonja, L., Picht, T., Ritter, P. 2020. The Language Connectome in Brain Tumor Patients. DFG, Project funding.
Cooperations
Picht, T., Fekonja, L. (PIs) 2019. Brain Roads. Interdisciplinary French-German project with Simatic, M with ESAD de Reims; Télécom SudParis - Institut polytechnique de Paris; Charité-Universitätsmedizin Berlin. https://entreformesetsignes.fr/la-recherche/programme-datavisualisation/brain-roads